REVIEW article
Front. Endocrinol.
Sec. Gut Endocrinology
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1610869
Mechanisms of Traditional Chinese Medicine Regulating Polycystic Ovary Syndrome through Gut Microbiota: A Review
Provisionally accepted
- Seventh People's Hospital of Shanghai, Shanghai, China
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Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder that adversely affects women's reproductive and metabolic health conditions. Recent studies have highlighted the significant contributory role of gut microbiota in the pathogenesis of PCOS, indicating a complex interplay between the microbiome and the syndrome's clinical manifestations. Given this connection, Traditional Chinese Medicine (TCM), a well-established therapeutic approach, has demonstrated potential efficacy in modulating gut microbiota and alleviating symptoms associated with PCOS. This review aims to summarize and analyze current research on the effects of TCM on gut microbiota in individuals with PCOS, exploring underlying mechanisms and relevant findings to provide insights for future clinical applications and improve understanding of TCM's role in managing PCOS.
Keywords: Polycystic Ovary Syndrome, Traditional Chinese Medicine, Gut Microbiota, mechanisms, Hyperandrogenism, Insulin Resistance, Inflammation
Received: 13 Apr 2025; Accepted: 18 Jul 2025.
Copyright: © 2025 Jiang, Wang, Hua, Tang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Heyue Li, Seventh People's Hospital of Shanghai, Shanghai, China
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