Functional Genomic Analysis | List of Frontiers open access articles

Original Research

Published on 29 Oct 2025

Deficits in medial prefrontal cortex parvalbumin expression and distraction-dependent memory in rats and mice in the sub-chronic phencyclidine model for schizophrenia

in Cellular Neurophysiology

Katie R. Landreth
Jacob Juty
Neveen Mansour
Patricia Radu
Jennifer Fletcher
Imane Benalla
Ben Grayson
Rasmus S. Petersen
Michael K. Harte
John Gigg

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1669050

497 views

Systematic Review

Published on 29 Oct 2025

The effectiveness of high-intensity interval training on cardiometabolic outcomes in middle-aged and elderly populations with chronic diseases: a systematic review and meta-analysis

in Exercise Physiology

Qiang Li
Gang Xu
Chunai Liu
Lina Gao
Hongli Yu

Frontiers in Physiology

doi 10.3389/fphys.2025.1669941

372 views

Original Research

Published on 29 Oct 2025

Gene expression profile in colon cancer therapeutic resistance and its relationship with the tumor microenvironment

in Network Bioinformatics

Priscila Galvão Doria
Gisele Vieira Rocha
Vanessa Dybal Bertoni
Roberto de Souza Batista dos Santos
Mariana Araújo-Pereira
Clarissa Gurgel

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1674179

466 views

Case Report

Published on 29 Oct 2025

Case Report: Delayed-type hypersensitivity reaction to meropenem in an elderly patient—successful management with imipenem-cilastatin

in Infectious Diseases: Pathogenesis and Therapy

Cuilin He
Maozhu Liu
Jiao Ye
Hong Zheng
Junjie Yang
Lingmei Huang

Frontiers in Medicine

doi 10.3389/fmed.2025.1671455

246 views

Original Research

Published on 29 Oct 2025

Major depressive disorders in children aged 5–14 years: a Global Burden of Disease analysis from the perspective of exercise psychology

in Children and Health

Wei Wei
Yongsheng Sun
Shuting Yin
Wei Lyu
Rui Liang

Frontiers in Public Health

doi 10.3389/fpubh.2025.1671222

255 views

Original Research

Published on 29 Oct 2025

Straw mulching-driven microbial relay enhances soil C–N coupling and cotton yield–quality synergy

in Crop and Product Physiology

Zhangshu Xie
Yeling Qin
Xiaodong Xie
Jiarui Li
Lijuan Zheng
Youhong Jiang
Xiaoju Tu
Aiyu Liu
Zhonghua Zhou

Frontiers in Plant Science

doi 10.3389/fpls.2025.1671192

209 views

Case Report

Published on 29 Oct 2025

Case Report: Spontaneous regression of extruded lumbar disc herniation following Chuzhen therapy over 3 years

in Family Medicine and Primary Care

Youpeng Hu
Ye-Hui Wang
Wenlong Guo
Shengxin Zhao
Peidong Qing
Shiming Xie
Xiaohong Fan

Frontiers in Medicine

doi 10.3389/fmed.2025.1674464

260 views

Original Research

Published on 29 Oct 2025

Single-cell atlas of human penile corpus cavernosum reveals cellular and functional heterogeneity of aging-related erectile dysfunction

in Reproduction

Bailing Zhang
Xueheng Zhao
Jian Cao
Zhizhong Liu
Xiaoyan Wang
Ran Li
Hao Bo
Kongrong Xu
Jingtao Guo

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1671482

363 views

Perspective

Published on 29 Oct 2025

A novel multi-layered immune structural model for peripheral blood immune scoring in cancer patients: perspective and hypothesis

in Cancer Immunity and Immunotherapy

Hao Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675411

338 views

Original Research

Published on 29 Oct 2025

Knockdown of TOP2A reverses cisplatin resistance in ovarian cancer by inhibiting EMT via ferroptosis mediated by the TP53/GPX4/SLC7A11 axis

in Cancer Immunity and Immunotherapy

Xinyue Liu
Junxia Wang
Yangyu Liu
Yan Han
Zhichao Qin
Yu Wang
Shanxiang Gao
Xinghua Li
Yuping Suo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675373

766 views

Systematic Review

Published on 29 Oct 2025

Impact of digital health technology-based nutritional interventions on the nutritional status of hemodialysis patients: a systematic review and meta-analysis

in Clinical Nutrition

Kai Zhang
Nan Zhang
Ruixue Wang
Shuimiao Wei
Cuiping Ni

Frontiers in Nutrition

doi 10.3389/fnut.2025.1681161

527 views

Case Report

Published on 29 Oct 2025

Case Report: Aspergillosis and Cyathostoma americana co-infection in the lower respiratory tract of a Harris’s Hawk (Parabuteo unicinctus)

in Veterinary Clinical, Anatomical, and Comparative Pathology

Susanne Rau
Oliver Krone
Wieland Schrödl
Jan Schinköthe

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1680843

886 views

Original Research

Published on 29 Oct 2025

Machine learning-based detection of cognitive decline using SSWTRT: classification performance and decision analysis

in Medicine and Public Health

Yuji Nozaki
Chihiro Kamohara
Ryota Abe
Taiki Ieda
Madoka Nakajima
Maki Sakamoto

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1689182

737 views

Correction

Published on 29 Oct 2025

Correction: Uncovering multilevel drivers of cancer disparities among Latinos in the United States

in Life-Course Epidemiology and Social Inequalities in Health

Amelie G. Ramirez
Edgar Munoz
Lorna Rodriguez-Rodriguez
Leon Bernal-Mizrachi
Patricia Chalela
Jose Aron Lopez
Paulo S. Pinheiro
Barbara Segarra-Vasquez
Gregory Talavera
Luis G. Carvajal-Carmona

Frontiers in Public Health

doi 10.3389/fpubh.2025.1686736

776 views

Original Research

Published on 29 Oct 2025

Renewable energy consumption optimization allocation strategy for a regional microgrid based on a shared energy storage mechanism

in Energy Storage

Hongde Ma
Weiqi Zhang
Ziqing Luo

Frontiers in Energy Research

doi 10.3389/fenrg.2025.1686684

713 views

Original Research

Published on 29 Oct 2025

Long-term trends in the burden of non-rheumatic calcific aortic valve disease in China from 1990 to 2021, with projections to 2050: results from the global burden of disease study

in Geriatric Medicine

Bin Jian
Zhen Li
Yu Huang
Zhixiong Wei
Gaoyang Zhao
Jun Fang

Frontiers in Medicine

doi 10.3389/fmed.2025.1690631

202 views

Articles

Deficits in medial prefrontal cortex parvalbumin expression and distraction-dependent memory in rats and mice in the sub-chronic phencyclidine model for schizophrenia

The effectiveness of high-intensity interval training on cardiometabolic outcomes in middle-aged and elderly populations with chronic diseases: a systematic review and meta-analysis

Gene expression profile in colon cancer therapeutic resistance and its relationship with the tumor microenvironment

Case Report: Delayed-type hypersensitivity reaction to meropenem in an elderly patient—successful management with imipenem-cilastatin

Major depressive disorders in children aged 5–14 years: a Global Burden of Disease analysis from the perspective of exercise psychology

Straw mulching-driven microbial relay enhances soil C–N coupling and cotton yield–quality synergy

Case Report: Spontaneous regression of extruded lumbar disc herniation following Chuzhen therapy over 3 years

Single-cell atlas of human penile corpus cavernosum reveals cellular and functional heterogeneity of aging-related erectile dysfunction

A novel multi-layered immune structural model for peripheral blood immune scoring in cancer patients: perspective and hypothesis

Knockdown of TOP2A reverses cisplatin resistance in ovarian cancer by inhibiting EMT via ferroptosis mediated by the TP53/GPX4/SLC7A11 axis

Impact of digital health technology-based nutritional interventions on the nutritional status of hemodialysis patients: a systematic review and meta-analysis

Case Report: Aspergillosis and Cyathostoma americana co-infection in the lower respiratory tract of a Harris’s Hawk (Parabuteo unicinctus)

Machine learning-based detection of cognitive decline using SSWTRT: classification performance and decision analysis

Correction: Uncovering multilevel drivers of cancer disparities among Latinos in the United States

Renewable energy consumption optimization allocation strategy for a regional microgrid based on a shared energy storage mechanism

Long-term trends in the burden of non-rheumatic calcific aortic valve disease in China from 1990 to 2021, with projections to 2050: results from the global burden of disease study

Major depressive disorders in children aged 5–14 years: a Global Burden of Disease analysis from the perspective of exercise psychology