Endocrinology

Skip to main content

Endocrinology

Endocrinology is a branch of medical science that focuses on the study of the endocrine system, which consists of glands that produce hormones. We cover a variety of topics in a continuously advancing field, presenting ongoing research which helps us better understand the mechanisms of hormone actions, as well as new diagnostic tools and therapeutic interventions.

The following Research Topics are led by experts in their field and contribute to the scientific understanding of endocrinology. These Research topics are published in the peer-reviewed journal Frontiers in Endocrinology, as open access articles.

Research Topics

Frontiers' Research Topics are peer-reviewed article collections around cutting-edge research themes.
Learn more about how Research topics work.

Two Asian trainer man and Overweight woman exercising training on treadmill in gym. Fat women take care of health and want to lose weight.

Exploring the Impact of Nutrition and Physical Activity on Sarcopenic Obesity

This research topic aims to explore the dynamic interplay between nutrition and physical activity in the prevention and management of sarcopenic obesity.

Fat infiltration of the heart. Fatty infiltration of the myocardium - fat cells infiltrating the cardiac tissue replacing myocytes with fibrosis. Fibrofatty myocardium

The Complex Phenotype of Diabetic Cardiomyopathy: Clinical Indicators and Novel Treatment Targets – Volume II

The this Research Topic highlights recent advances and discoveries in the progression and treatment of diabetic cardiomyopathy.

3d rendered, medically accurate illustration of fatcells

Exploring Endocrine and Nutritional Metabolism's Role in Tumor Development and Progression

This Research Topic aims to elucidate the intricate relationship between changes in endocrine and nutritional metabolism and tumor development.

Concept children diabetes children with glucometer learning to check blood sugar level at home. Learn to use a glucometer. Education of diabetic kids, at hospital

The Problem of Childhood Hypoglycemia - Volume III

This Research Topic aims to align basic science understanding of the biology of glucose regulation, provide rational understanding of thresholds of hypoglycemia, and develop rational therapy strategies in severe disorders of hypoglycemia.

Loggerhead Sea Turtle at rehabilitation facility

Responses to Chronic Stress in Vertebrate Animals: From Molecules to Behavior

This Research Topic aims to gather articles that address the conceptual definitions of chronic stress in vertebrates, focusing on aspects such as duration, severity, repeatability, predictability, and controllability of experimental protocols.

Microbiome intestine factories and microbiota. Gut health 3d render. Microvilli with factories in intestine

Impact of Dietary Factors on Human Gut Microbiota and Gastrointestinal Endocrinology

This Research Topic aims to deepen understanding of how dietary constituents interact with gut microbiota to influence metabolic health.

Female doctor measuring waist of overweight woman with measuring tape in clinic

Hyperphagia in Syndromic and Hypothalamic Obesity: Mechanisms, Consequences, and Interventions

This Research Topic explores hyperphagia assessment, its metabolic consequences in obesity, and treatments such as MC4R-targeting medications, GLP-1 receptor agonists, and behavioral interventions to manage emotional and behavioral responses to hunger.

Ultrasound diagnostics of thyroid gland. Endocrinologist making ultrasonography to senior female patient at ultrasound office of medical clinic

Thyroid Disorders Associated with Cancer Immunotherapy

This Research Topic invites manuscripts on thyroid dysfunction in cancer immunotherapy, covering mechanisms, clinical challenges, predictive markers, management strategies, and long-term care to improve outcomes for patients undergoing immunotherapy.

Human growth hormone (hGH, Somatotropin) protein. Natural hormone that is used both as a medicine and as a doping agent. 3D rendering based on protein data bank entry 1hwg. .

Long-acting Growth Hormone Therapy in Pediatric Growth Hormone Deficiency

This Research Topic aims to evaluate the efficacy, safety, and adherence to long-acting growth hormone therapy compared to daily GH injections in pediatric patients with GHD.

Gynecologist doctor consulting patient showing uterus anatomy model

The Systemic and Metabolic effects of 17-Beta Estradiol

This Research Topic aims to elucidate how estradiol guides developmental trajectories and maintains health, focusing on themes such as metabolic programming, neuroendocrine maturation, and the establishment of critical physiological systems.

Lumbar spine X-ray showing straight spine without radiographic sign of spinal infection or metastasis.

Bone Metastases in Endocrine Cancers: Advances in Diagnosis, Treatment, and Prevention

This Research Topic aims to delve deeper into the evolving dynamics of life expectancy and treatment efficacy in MBD within the sphere of endocrine oncology.

Chronic glomerulonephritis, light micrograph, photo under microscope. High magnification

Novel Strategies for the Clinical Management of Cardiovascular-Kidney-Metabolic Syndrome

This Research Topic aims to foster a deeper understanding of comprehensive treatment regimes, pharmacotherapy advances, and outcome prediction methodologies within the CKM spectrum.

CTLA-4 (Cytotoxic T-lymphocyte-associated protein 4, CD152) protein. CTLA4 blocking antibodies are used in cancer therapy (immune checkpoint blockade therapy). 3D rendering.

Association of Diabetes Mellitus with Cognitive Impairment and Neurological Disorders Vol. 2

This research topic aims to focus on several aspects of the connections between diabetes and cognition impairment in both animal and human models.

Human colon cancer cells with the cell nuclei stained red and the protein E-cadherin stained green. E-cadherin is a cell adhesion molecule and its loss signals a process known as the epithelial-mesenchymal transition in which cells acquire the ability to migrate and become invasive.

Epithelial-Mesenchymal Transition (EMT) in Endocrine Disorders: Mechanisms, Hormonal Regulation, and Therapeutic Potential

This Research Topic aims to explore the role of EMT and EMP in endocrine health and disease, focusing on how hormonal regulation affects cellular transitions in both physiological and pathological contexts.

Senior man taking box on pills from pharmacy shelves to buy medicine and healthcare treatment, talking to pharmacist about pharmaceutical products. Buying supplements and medication.

Impact of New Vitamin D Guidelines on Pediatric and Adult Health: Insights, Evidence, and Implications

This Research Topic seeks to explore the implications of the new vitamin D guidelines, addressing both their evidence base and real-world impact.

Diabetes is a metabolic disorder caused by high levels of blood sugar, Glucose and insulin molecules in the blood, 3d illustration

Interplay between Glucose and Lipid Homeostasis in Metabolic Health

This Research Topic aims to advance our understanding of the complex interactions between glucose and lipid homeostasis and their collective impact on metabolic health.

Thyroid cancer: Psammoma bodies are granules of concentric layers of calcium commonly seen in papillary carcinoma such as in this case. An intranuclear inclusion is also noted (lower right)

Molecular Characterization of Thyroid Lesions in the Era of “Next Generation” Techniques: Volume III

This Research Topic showcases the application of novel techniques in characterizing thyroid tumors for diagnostic, prognostic, or predictive purposes.

Diabetes test. Pregnant women checking sugar level with glucometer.Gestational diabetes.

Postpartum BMI and Cardiovascular-Kidney Metabolic Syndrome: Navigating Weight Management Post-GDM

This research topic explores the intricate relationship between postpartum BMI trajectories and CKM, addressing key gaps in understanding how targeted weight management strategies can reduce complications in this high-risk population.

Astrocyte and blood vessel, 3D illustration. Astrocytes, brain glial cells, also known as astroglia, connect neuronal cells to blood vessels

Endocrinology of Aging: Advances in Molecular Biology and Metabolic Diseases

This Research Topic explores the molecular mechanisms linking endocrine aging and metabolic diseases.

Medical device for glucose check. Continuous glucose monitoring pod. Modern wireless technology.

Technologies for Diabetes, volume III

This Research Topic explores diabetes technology, including insulin pumps, CGM systems, closed-loop control, telemedicine, and technology education.

Two Asian trainer man and Overweight woman exercising training on treadmill in gym. Fat women take care of health and want to lose weight.

Exploring the Impact of Nutrition and Physical Activity on Sarcopenic Obesity

This research topic aims to explore the dynamic interplay between nutrition and physical activity in the prevention and management of sarcopenic obesity.

Fat infiltration of the heart. Fatty infiltration of the myocardium - fat cells infiltrating the cardiac tissue replacing myocytes with fibrosis. Fibrofatty myocardium

The Complex Phenotype of Diabetic Cardiomyopathy: Clinical Indicators and Novel Treatment Targets – Volume II

The this Research Topic highlights recent advances and discoveries in the progression and treatment of diabetic cardiomyopathy.

3d rendered, medically accurate illustration of fatcells

Exploring Endocrine and Nutritional Metabolism's Role in Tumor Development and Progression

This Research Topic aims to elucidate the intricate relationship between changes in endocrine and nutritional metabolism and tumor development.

Concept children diabetes children with glucometer learning to check blood sugar level at home. Learn to use a glucometer. Education of diabetic kids, at hospital

The Problem of Childhood Hypoglycemia - Volume III

This Research Topic aims to align basic science understanding of the biology of glucose regulation, provide rational understanding of thresholds of hypoglycemia, and develop rational therapy strategies in severe disorders of hypoglycemia.

Loggerhead Sea Turtle at rehabilitation facility

Responses to Chronic Stress in Vertebrate Animals: From Molecules to Behavior

This Research Topic aims to gather articles that address the conceptual definitions of chronic stress in vertebrates, focusing on aspects such as duration, severity, repeatability, predictability, and controllability of experimental protocols.

Microbiome intestine factories and microbiota. Gut health 3d render. Microvilli with factories in intestine

Impact of Dietary Factors on Human Gut Microbiota and Gastrointestinal Endocrinology

This Research Topic aims to deepen understanding of how dietary constituents interact with gut microbiota to influence metabolic health.

Female doctor measuring waist of overweight woman with measuring tape in clinic

Hyperphagia in Syndromic and Hypothalamic Obesity: Mechanisms, Consequences, and Interventions

This Research Topic explores hyperphagia assessment, its metabolic consequences in obesity, and treatments such as MC4R-targeting medications, GLP-1 receptor agonists, and behavioral interventions to manage emotional and behavioral responses to hunger.

Ultrasound diagnostics of thyroid gland. Endocrinologist making ultrasonography to senior female patient at ultrasound office of medical clinic

Thyroid Disorders Associated with Cancer Immunotherapy

This Research Topic invites manuscripts on thyroid dysfunction in cancer immunotherapy, covering mechanisms, clinical challenges, predictive markers, management strategies, and long-term care to improve outcomes for patients undergoing immunotherapy.

Human growth hormone (hGH, Somatotropin) protein. Natural hormone that is used both as a medicine and as a doping agent. 3D rendering based on protein data bank entry 1hwg. .

Long-acting Growth Hormone Therapy in Pediatric Growth Hormone Deficiency

This Research Topic aims to evaluate the efficacy, safety, and adherence to long-acting growth hormone therapy compared to daily GH injections in pediatric patients with GHD.

Gynecologist doctor consulting patient showing uterus anatomy model

The Systemic and Metabolic effects of 17-Beta Estradiol

This Research Topic aims to elucidate how estradiol guides developmental trajectories and maintains health, focusing on themes such as metabolic programming, neuroendocrine maturation, and the establishment of critical physiological systems.

Lumbar spine X-ray showing straight spine without radiographic sign of spinal infection or metastasis.

Bone Metastases in Endocrine Cancers: Advances in Diagnosis, Treatment, and Prevention

This Research Topic aims to delve deeper into the evolving dynamics of life expectancy and treatment efficacy in MBD within the sphere of endocrine oncology.

Chronic glomerulonephritis, light micrograph, photo under microscope. High magnification

Novel Strategies for the Clinical Management of Cardiovascular-Kidney-Metabolic Syndrome

This Research Topic aims to foster a deeper understanding of comprehensive treatment regimes, pharmacotherapy advances, and outcome prediction methodologies within the CKM spectrum.

CTLA-4 (Cytotoxic T-lymphocyte-associated protein 4, CD152) protein. CTLA4 blocking antibodies are used in cancer therapy (immune checkpoint blockade therapy). 3D rendering.

Association of Diabetes Mellitus with Cognitive Impairment and Neurological Disorders Vol. 2

This research topic aims to focus on several aspects of the connections between diabetes and cognition impairment in both animal and human models.

Human colon cancer cells with the cell nuclei stained red and the protein E-cadherin stained green. E-cadherin is a cell adhesion molecule and its loss signals a process known as the epithelial-mesenchymal transition in which cells acquire the ability to migrate and become invasive.

Epithelial-Mesenchymal Transition (EMT) in Endocrine Disorders: Mechanisms, Hormonal Regulation, and Therapeutic Potential

This Research Topic aims to explore the role of EMT and EMP in endocrine health and disease, focusing on how hormonal regulation affects cellular transitions in both physiological and pathological contexts.

Senior man taking box on pills from pharmacy shelves to buy medicine and healthcare treatment, talking to pharmacist about pharmaceutical products. Buying supplements and medication.

Impact of New Vitamin D Guidelines on Pediatric and Adult Health: Insights, Evidence, and Implications

This Research Topic seeks to explore the implications of the new vitamin D guidelines, addressing both their evidence base and real-world impact.

Diabetes is a metabolic disorder caused by high levels of blood sugar, Glucose and insulin molecules in the blood, 3d illustration

Interplay between Glucose and Lipid Homeostasis in Metabolic Health

This Research Topic aims to advance our understanding of the complex interactions between glucose and lipid homeostasis and their collective impact on metabolic health.

Thyroid cancer: Psammoma bodies are granules of concentric layers of calcium commonly seen in papillary carcinoma such as in this case. An intranuclear inclusion is also noted (lower right)

Molecular Characterization of Thyroid Lesions in the Era of “Next Generation” Techniques: Volume III

This Research Topic showcases the application of novel techniques in characterizing thyroid tumors for diagnostic, prognostic, or predictive purposes.

Diabetes test. Pregnant women checking sugar level with glucometer.Gestational diabetes.

Postpartum BMI and Cardiovascular-Kidney Metabolic Syndrome: Navigating Weight Management Post-GDM

This research topic explores the intricate relationship between postpartum BMI trajectories and CKM, addressing key gaps in understanding how targeted weight management strategies can reduce complications in this high-risk population.

Astrocyte and blood vessel, 3D illustration. Astrocytes, brain glial cells, also known as astroglia, connect neuronal cells to blood vessels

Endocrinology of Aging: Advances in Molecular Biology and Metabolic Diseases

This Research Topic explores the molecular mechanisms linking endocrine aging and metabolic diseases.

Medical device for glucose check. Continuous glucose monitoring pod. Modern wireless technology.

Technologies for Diabetes, volume III

This Research Topic explores diabetes technology, including insulin pumps, CGM systems, closed-loop control, telemedicine, and technology education.