Hypertension is a major global health challenge, affecting millions and serving as a key risk factor for cardiovascular and renal diseases. While endocrine hypertension—driven by hormonal imbalances such as those seen in primary aldosteronism, Cushing’s syndrome, and pheochromocytoma—accounts for 5–10% of cases, endocrine pathways play a critical role in regulating arterial pressure in all forms of hypertension. Recent advances have shed light on the broader endocrine mechanisms influencing blood pressure regulation, including the roles of adrenal hormones, the renin-angiotensin-aldosterone system (RAAS), insulin resistance, and obesity-related hormonal dysregulation.
This Research Topic aims to explore the complex interplay between endocrine pathways and hypertension, emphasizing both molecular mechanisms and clinical implications. By bridging basic research with clinical applications, this collection seeks to provide a deeper understanding of how hormonal and metabolic pathways contribute to the onset, progression, and treatment of hypertension.
We invite submissions of original research, reviews, and clinical studies that address the endocrine dimensions of hypertension. Topics of interest include, but are not limited to:
• Endocrine Pathways in Hypertension: Investigations into hormonal and metabolic pathways influencing blood pressure regulation, including adrenal, thyroid, and pancreatic contributions.
• Genetic and Molecular Insights: Studies on genetic mutations, receptor signaling, and cellular pathways impacting endocrine-related hypertension.
• Clinical Management of Hypertension: Evaluations of treatment strategies, patient outcomes, and the role of hormonal modulation in managing hypertension.
• Diagnostic Innovations: Development of novel diagnostic approaches to better identify endocrine contributions to hypertensive disorders, including biochemical and imaging advancements.
• Therapeutic Strategies: Exploration of pharmacological and non-pharmacological interventions targeting endocrine mechanisms in hypertension.
• Hypertension and Metabolic Disorders: Insights into the bidirectional relationship between hypertension, insulin resistance, and obesity-related hormonal dysregulation.
This Research Topic aims to foster collaboration among endocrinologists, cardiologists, and researchers by providing a platform to explore the endocrine underpinnings of hypertension. By gathering cutting-edge research and expert perspectives, this collection seeks to promote innovative approaches to the diagnosis and treatment of hypertension, ultimately improving patient outcomes.
Article types and fees
This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:
Brief Research Report
Case Report
Clinical Trial
Editorial
FAIR² Data
FAIR² DATA Direct Submission
General Commentary
Hypothesis and Theory
Methods
Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.
Article types
This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
