CORRECTION article

Front. Cell Dev. Biol., 23 February 2022

Sec. Cancer Cell Biology

Volume 10 - 2022 | https://doi.org/10.3389/fcell.2022.841792

Corrigendum: GPER1 Silencing Suppresses the Proliferation, Migration, and Invasion of Gastric Cancer Cells by Inhibiting PI3K/AKT–Mediated EMT

  • 1. Department of General Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China

  • 2. Department of General Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China

  • 3. Department of Gastroenterology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China

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Error in Figure

In the original article, there was a mistake in Figures 3, 4 as published. In Figures 3D, 4C, we put the wrong picture due to carelessness. The corrected Figures 3, 4 appear below.

FIGURE 3

FIGURE 3

GPER1 knockdown impairs the proliferation of AGS and MGC-803 cells. (A) CCK-8 and (B) Edu assays were used to evaluate the proliferation of AGS and MGC-803 cells after transfection with siGPER1 for 48 h; (C) Flow cytometry and (D) CDK4 and cyclin D1 protein levels were used to analyze the cell cycle of AGS and MGC-803 cells after transfection with siGPER1 for 48 h. Control: cells without transfection; GPER1, cells transfected with GPER1 siRNA; 740Y-P, cells treated with 740Y-P; GPER1 + 740Y-P, cells transfected GPER1 siRNA and then treated with 740Y-P. Results were shown as mean ± SD of three independent experiments, each experiment was performed in triplicate. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

FIGURE 4

FIGURE 4

GPER1 knockdown impairs the migration and invasion of AGS and MGC-803 cells. (A) Cell mobility was detected by wound healing assay; (B) cell migration and (C) invasion were detected by transwell assays; (D). Western blot analysis of matrix metalloproteinase 9 (MMP9) and MMP2 protein expression. GAPDH was used as a loading control. Control, cells without transfection; GPER1, cells transfected with GPER1 siRNA; 740Y-P, cells treated with 740Y-P; GPER1 + 740Y-P, cells transfected GPER1 siRNA and then treated with 740Y-P. Results were shown as mean ± SD of three independent experiments, each experiment was performed in triplicate. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

GPER1, EMT, migration, invasion, gastric cancer

Citation

Xu E, Xia X, Jiang C, Li Z, Yang Z, Zheng C, Wang X, Du S, Miao J, Wang F, Wang Y, Lu X and Guan W (2022) Corrigendum: GPER1 Silencing Suppresses the Proliferation, Migration, and Invasion of Gastric Cancer Cells by Inhibiting PI3K/AKT–Mediated EMT. Front. Cell Dev. Biol. 10:841792. doi: 10.3389/fcell.2022.841792

Received

22 December 2021

Accepted

24 January 2022

Published

23 February 2022

Volume

10 - 2022

Edited by

Xing Huang, Zhejiang University, China

Updates

Copyright

*Correspondence: Xuefeng Xia, ; Xiaofeng Lu, ; Wenxian Guan,

This article was submitted to Cancer Cell Biology, a section of the journal Frontiers in Cell and Developmental Biology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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