Inappropriate and excessive use of chemicals leads to several negative effects on One Health. Therefore, research on alternative measures of pest control is urgent and necessary. Moreover, the United Nations 2030 agenda emphasizes the objective of achieving food security and promoting sustainable agriculture. Thus, the use of biological control is highly necessary. In this context, microbial control using fungi stands out. Some specific fungi are natural enemies of nematodes, as the fungi consume the nematodes. These carnivorous fungi are known as nematophagous fungi (NF).
NF are present in almost all taxonomic groups of the Fungi kingdom and can be classified into five groups: nematode-trapping/predators, opportunistic or ovicidal, endoparasites, toxin-producing fungi, and producers of special attack devices (Soares et al., 2018).
Those microorganisms have biotechnological interests, beyond biological control. Furthermore, the production of enzymes and nanoparticles derived from these organisms that have proven nematicidal activity is highlighted (Barbosa et al., 2019; Soares et al., 2023). Thus, in this Research Topic, Al-Ani et al. reviewed the role of NF in biotechnology and sustainable agriculture. They divided NF into two types according to the mechanisms that affect nematodes: direct (ectoparasites, endoparasites, cyst, or egg parasites producing toxins, and producers of special attack devices) or indirect effects (paralyzing toxins that affect the life cycle of nematodes). In addition, the authors discussed some molecular mechanisms of NF regarding the adaptation of NF to the environment and their action on nematodes.
One of the most prominent NF as a product and in research for the control of parasitic nematodes of plants of interest is Pochonia chlamydosporia. This opportunistic fungus has the ability to grow on chitosan as its only nutrient source. Chitosan is a polysaccharide generated from the N-deacetylated form of chitin. In addition, it is effective in the control of plant pests and diseases. In this Research Topic, Lopez-Nuñes et al. discuss the beneficial endophytic action that P. chlamydosporia performs on plants and how the combined use of chitosan and nematophagous fungi could be a novel strategy for the biological control of nematodes and other root pathogens.
Still regarding P. chlamydosporia, Ciancio et al. developed two models to simulate the interactions between the fungus and the root-knot nematode Meloidogyne incognita in a rhizosphere microcosm. Using complex models, these authors sought to describe the biocontrol interaction between P. chlamydosporia and M. incognita. Thus, they observed that non-parasitic fungal behavior affects biocontrol efficacy by a further density-independent host regulation mechanism.
On the other hand, for adequate production of NF, several parameters must be evaluated and optimized. Therefore, aspects of fermentation, formulation, predation, and half-life are important. In this Research Topic, Courtine et al. evaluated, over the course of two decades of laboratory culture, a strain of Drechmeria coniospora. They observed that, after that period, D. coniospora became more virulent during its infection of the nematode model Caenorhabditis elegans. They noticed that compared to the original isolate (Swe1), the cryo-archived strain (Swe3) was faster in killing the nematode. They suggested that a small number of non-synonymous mutations in protein-coding genes were responsible for such action.
Statements
Author’s note
Fabio Ribeiro Braga: Scholarship CNPq.
Author contributions
FS: Writing – original draft, Writing – review & editing. LA-M: Writing – review & editing. FB: Writing – review & editing.
Acknowledgments
The authors thank the financial support from the CAPES, CNPq, FAPEMIG, and FAPES agencies.
Conflict of interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Publisher’s note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
References
1
BarbosaA. C. M. S.SilvaL. P. C.FerrazC. M.TobiasF. L.de AraújoJ. V.LoureiroB.et al. (2019). Nematicidal activity of silver nanoparticles from the fungus Duddingtonia flagrans. Int. J. Nanomedicine14, 2341–2348. doi: 10.2147/IJN.S193679
2
SoaresF. E. F.FerreiraJ. M.GenierH. L. A.Al-AniL. K. T.Aguilar-MarcelinoL. (2023). Biological control 2.0: Use of nematophagous fungi enzymes for nematode control. J. Nat. Pestic. Res.4, 100025. doi: 10.1016/j.napere.2023.100025
3
SoaresF. E. F.SufiateB. L.de QueirozJ. H. (2018). Nematophagous fungi: Far beyond the endoparasite, predator and ovicidal groups. Agric. Nat. Resour.52 (1), 1–8. doi: 10.1016/j.anres.2018.05.010
Summary
Keywords
nematophagous fungi, nematode, biological control, metabolites, nematicidal
Citation
Soares FEF, Aguilar-Marcelino L and Braga FR (2024) Editorial: Nematophagous fungi as nematode control agents. Front. Fungal Biol. 4:1353132. doi: 10.3389/ffunb.2023.1353132
Received
09 December 2023
Accepted
22 December 2023
Published
17 January 2024
Volume
4 - 2023
Edited and reviewed by
Chengshu Wang, Chinese Academy of Sciences (CAS), China
Updates
Copyright
© 2024 Soares, Aguilar-Marcelino and Braga.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Filippe Elias de Freitas Soares, filippe.soares@ufla.br
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.