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Front. Immunol., 29 July 2020 | https://doi.org/10.3389/fimmu.2020.01650

Corrigendum: PSORI-CM02 Formula Increases CD4+ Foxp3+ Regulatory T Cell Frequency and Ameliorates Imiquimod-Induced Psoriasis in Mice

Haiming Chen1,2,3,4, Huazhen Liu1,3,4, Chuanjian Lu1,3,4,5*, Maojie Wang1,3,4, Xiong Li1,3,4, Hui Zhao6,7, Yuhong Yan1,3, Wanling Yu1,3,4, Ling Han1,3,4,5* and Zhenhua Dai1,3,4*
  • 1The Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China
  • 2Postdoctoral Programme, Guangzhou University of Chinese Medicine, Guangzhou, China
  • 3Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China
  • 4Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China
  • 5Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangzhou, China
  • 6Key Laboratory for Regenerative Medicine, Ministry of Education, Faculty of Medicine, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China
  • 7Kunming Institute of Zoology Chinese Academy of Sciences-The Chinese University of Hong Kong Joint Laboratory of Bioresources and Molecular Research of Common Diseases, Hong Kong, China

A Corrigendum on:
PSORI-CM02 Formula Increases CD4+ Foxp3+ Regulatory T Cell Frequency and Ameliorates Imiquimod-Induced Psoriasis in Mice

by Chen, H., Liu, H., Lu, C., Wang, M., Li, X., Zhao, H., et al. (2018). Front. Immunol. 8:1767. doi: 10.3389/fimmu.2017.01767

In the original article, there was a mistake in the legend for Figure 6 as published. Instead of “n = 3,” the caption should read “n = 6.”

In addition, there was a mistake in Figure 6A as published. The fifth diagram in the lower panel of Figure 6A was mistakenly duplicated from the third diagram in the upper panel. Moreover, we have now used the same quadrants for all groups of Spleen vs. Lymph nodes to increase accuracy. The slight changes in quadrants resulted in slight changes in Figure 6B. The correct Figure 6 and legend appear below.

FIGURE 6
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Figure 6. PSORI-CM02 induces CD4+ Foxp3+ regulatory T cells (Tregs) in imiquimod (IMQ)-induced psoriasis-like mice. Effects of PSORI-CM02 on CD4+Foxp3+ Treg frequency in spleens and lymph nodes of IMQ-induced psoriasis-like mice were observed. Spleen and lymph node cells were isolated from IMQ-induced psoriasis-like mice seven days after treatments with PSORI-CM02 or dexamethasone acetate (DXM). To quantify CD4+ Foxp3+ Tregs, cells were stained for CD4 surface and intracellular Foxp3 makers (A) and CD4+ Foxp3+ Treg frequency in spleen and lymph node were shown (B). Data shown are the mean values ± SD (n = 6, ##P < 0.01 vs. control group, and **P < 0.01 vs. vehicle group).

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Keywords: psoriasis, inflammation, immunoregulation, regulatory T cell, PSORI-CM02

Citation: Chen H, Liu H, Lu C, Wang M, Li X, Zhao H, Yan Y, Yu W, Han L and Dai Z (2020) Corrigendum: PSORI-CM02 Formula Increases CD4+ Foxp3+ Regulatory T Cell Frequency and Ameliorates Imiquimod-Induced Psoriasis in Mice. Front. Immunol. 11:1650. doi: 10.3389/fimmu.2020.01650

Received: 23 May 2020; Accepted: 22 June 2020;
Published: 29 July 2020.

Edited and reviewed by: Pietro Ghezzi, Brighton and Sussex Medical School, United Kingdom

Copyright © 2020 Chen, Liu, Lu, Wang, Li, Zhao, Yan, Yu, Han and Dai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Chuanjian Lu, luchuanjian888@vip.sina.com; Ling Han, linghan36@163.com; Zhenhua Dai, zdai2009@hotmail.com

These authors have contributed equally to this work