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Front. Immunol., 28 October 2020 |

Corrigendum: Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression

Bernhard Ryffel1,2*, Feng Huang1, Pauline Robinet2, Corine Panek2, Isabelle Couillin2, François Erard2, Julie Piotet2, Marc Le Bert2, Claire Mackowiak2, Marbel Torres Arias3, Isabelle Dimier-Poisson4 and Song Guo Zheng5*
  • 1Department of Clinical Immunology, Sun Yat-sen University Third Affiliated Hospital, Guangzhou, China
  • 2INEM UMR 7355 CNRS and University of Orleans, Orléans, France
  • 3Immunology and Virology Laboratory, Nanoscience and Nanotechnology Center, Universidad de las Fuerzas Armadas, ESPE, Sangolquí, Ecuador
  • 4UMR 1282 Infectiologie Animale et Santé Publique, Université de Tours -INRA, Tours, France
  • 5Department of Internal Medicine, Ohio State College of Medicine, Columbus, OH, United States

Corrigendum on
Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression

by Ryffel, B., Huang, F., Robinet, P., Panek, C., Couillin, I., Erard, F., et al. (2019). Front. Immunol. 10:702. doi: 10.3389/fimmu.2019.00702

In the published article, there was an error in affiliation 2. Instead of “UMR 7355 Université-CNRS INEM, Orléans, France and IDM, University of Cape Town, South Africa”, it should be “INEM UMR 7355 CNRS and University of Orleans, Orléans, France.”

In addition, the wrong microscopic plates were inserted into Figures 5E and F. The corrected Figure 5 appears below.


Figure 5. IL-22 confers protection in IL-33R/ST2 deficient mice upon T. gondii infection Infection by T. gondii infection induces enhanced IL22 mRNA and protein expression in ST2 deficient mice (A,B) and increased IL-33 expression (B). Administration of rmIL-22 reduces MPO activity, CXCL1/KC levels, neutrophil recruitment (C) and severity of ileitis in B6 mice (D). By contrast, IL-22 antibody blockade in IL-33R/ST2 deficient mice increased MPO activity, CXCL1/KC levels and neutrophil recruitment (E) and enhanced severity of ileitis (F). Analysis at day 7 post-infection. Values are representative of two independent experiments.

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Keywords: Toxoplasma gondii, IL-33/ST2 receptor, neutralizing antibody, IL-22, parasite-induced ileitis, innate immunity

Citation: Ryffel B, Huang F, Robinet P, Panek C, Couillin I, Erard F, Piotet J, Le Bert M, Mackowiak C, Torres Arias M, Dimier-Poisson I and Zheng SG (2020) Corrigendum: Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression. Front. Immunol. 11:592865. doi: 10.3389/fimmu.2020.592865

Received: 08 August 2020; Accepted: 25 August 2020;
Published: 28 October 2020.

Edited and reviewed by: Fang-Ping Huang, Shenzhen University, China

Copyright © 2020 Ryffel, Huang, Robinet, Panek, Couillin, Erard, Piotet, Le Bert, Mackowiak, Torres Arias, Dimier-Poisson and Zheng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Bernhard Ryffel,; Song Guo Zheng,

These authors have contributed equally to this work