@ARTICLE{10.3389/fimmu.2021.753558, AUTHOR={Sherwood, Karen R. and Nicholl, David D. M. and Fenninger, Franz and Wu, Vivian and Wong, Paaksum and Benedicto, Vince and Cina, Davide P. and Wang, Meng and Pobran, Taylor D. and De Marco, Mari L. and Márquez, Anna Citlali and Jassem, Agatha N. and Sekirov, Inna and Morshed, Muhammad G. and Bardi, Mohammad and Sekhon, Mypinder and Keown, Paul and Kadatz, Matthew and Lan, James H.}, TITLE={Comprehensive Immune Profiling of a Kidney Transplant Recipient With Peri-Operative SARS-CoV-2 Infection: A Case Report}, JOURNAL={Frontiers in Immunology}, VOLUME={12}, YEAR={2021}, URL={https://www.frontiersin.org/articles/10.3389/fimmu.2021.753558}, DOI={10.3389/fimmu.2021.753558}, ISSN={1664-3224}, ABSTRACT={To date there is limited data on the immune profile and outcomes of solid organ transplant recipients who encounter COVID-19 infection early post-transplant. Here we present a unique case where the kidney recipient’s transplant surgery coincided with a positive SARS-CoV-2 test and the patient subsequently developed symptomatic COVID-19 perioperatively. We performed comprehensive immunological monitoring of cellular, proteomic, and serological changes during the first 4 critical months post-infection. We showed that continuation of basiliximab induction and maintenance of triple immunosuppression did not significantly impair the host’s ability to mount a robust immune response against symptomatic COVID-19 infection diagnosed within the first week post-transplant.} }