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Front. Microbiol. | doi: 10.3389/fmicb.2018.03067

Antimicrobial susceptibility and genomic structure of Arcobacter skirrowii isolates

 Ingrid Hänel1,  Helmut Hotzel1, Herbert Tomaso1 and  Anne Busch1*
  • 1Institut für bakterielle Infektionen und Zoonosen, Friedrich Loeffler Institut, Germany

Campylobacter spp. are considered the most common foodborne bacterial cause of gastroenteritis in the world. The family Campylobacteraceae includes the genus Arcobacter with the three species, A. butzleri, A. cryaerophilus and A. skirrowii as emergent enteropathogens and potential zoonotic agents. Here, we generated, analyzed and characterized genome sequences of Arcobacter that were isolated from water poultry on farms in Germany. Isolates were cultured, identified by MALDI-TOF MS and identification was verified with PCR.
Antibiotic susceptibility testing of isolates was carried out with erythromycin, ciprofloxacin, doxycycline, tetracycline, gentamicin and streptomycin using the gradient strip method (E-test). We also sequenced the whole genomes and predicted antibiotic resistance determinants, virulence factors, plasmids and performed a phylogenetic analysis to determine the genetic relatedness of these isolates.

Keywords: Arcobacter butzleri, Arcobacter skirrowii, antibiotic, Genome, antibiotic susceptibility, Animal Health

Received: 15 Aug 2018; Accepted: 28 Nov 2018.

Edited by:

Marcelo Tolmasky, California State University, Fullerton, United States

Reviewed by:

Greta Gölz, Freie Universität Berlin, Germany
German M. Traglia, Universidad de Buenos Aires, Argentina  

Copyright: © 2018 Hänel, Hotzel, Tomaso and Busch. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dr. Anne Busch, Institut für bakterielle Infektionen und Zoonosen, Friedrich Loeffler Institut, Jena, Germany,