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Original Research ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Microbiol. | doi: 10.3389/fmicb.2019.01997

Buckwheat hull extracts inhibit Aspergillus flavus growth and AFB1 biosynthesis

 Chiara Nobili1, agnese de acutis1,  Massimo Reverberi2*, cristiano bello3, gian paolo leone1, domenico palumbo1, fausta natella3, silvia procacci1,  slaven zjalic4 and andrea brunori1
  • 1Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), Italy
  • 2Sapienza University of Rome, Italy
  • 3Council for Agricultural and Economics Research, Italy
  • 4Department of Ecology, Agriculture & Aquaculture, Center for Interdisciplinary Marine and Maritime Reseach, University of Zadar, Croatia

Fungal contamination poses at risk the whole food production chain - from farm to fork - with potential negative impact on human health. So far, the insurgence of pathogens has been restrained by the use of chemical compounds, whose residues have gradually accumulated determining toxic effects in the environment. Modern innovative techniques imply the use of natural and eco-sustainable bioactive plant molecules as pathogens and pests-control agents. These may be profitably recovered in large amounts at the end of industrial milling processes. This is the case of the non-digestible hull of common buckwheat (Fagopyrum esculentum Moench), a natural source of polyphenols, tocopherols, phytosterols and fatty acids. We extract these compounds from the hull of buckwheat; apply them to Aspergillus flavus - aflatoxin producer - under in vitro conditions, checking their ability to inhibit fungal growth and aflatoxin biosynthesis. Moreover, a solvent free method implying the adoption of supercritical CO2 as solvent was set up to extract lipophilic molecules from the buckwheat’ hulls. Positive results in controlling fungal growth and aflatoxin biosynthesis let infer that the extracts could be further tested also under in vivo conditions

Keywords: Plant waste, natural compound, aflatoxin, Disease control, Aspergillus

Received: 01 Jul 2019; Accepted: 15 Aug 2019.

Copyright: © 2019 Nobili, de acutis, Reverberi, bello, leone, palumbo, natella, procacci, zjalic and brunori. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Mx. Massimo Reverberi, Sapienza University of Rome, Rome, Italy, massimo.reverberi@uniroma1.it