@ARTICLE{10.3389/fmicb.2020.573430, AUTHOR={Shen, Lishuang and Dien Bard, Jennifer and Biegel, Jaclyn A. and Judkins, Alexander R. and Gai, Xiaowu}, TITLE={Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country}, JOURNAL={Frontiers in Microbiology}, VOLUME={11}, YEAR={2020}, URL={https://www.frontiersin.org/articles/10.3389/fmicb.2020.573430}, DOI={10.3389/fmicb.2020.573430}, ISSN={1664-302X}, ABSTRACT={Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the city-, state-, and country-levels, and temporal transmissions. This points to the effectiveness of existing travel restriction policies and public health measures in reducing the transmission of SARS-CoV-2.} }