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REVIEW article

Front. Microbiol. | doi: 10.3389/fmicb.2021.686977

Ribosome Biogenesis in Archaea Provisionally accepted The final, formatted version of the article will be published soon. Notify me

  • 1Department of Molecular Medicine, Faculty of Pharmacy and Medicine, Sapienza University of Rome, Italy
  • 2University of Regensburg, Germany

Making ribosomes is a major cellular process essential for the maintenance of functional ribosome homeostasis and to ensure appropriate gene expression. Strikingly, although ribosomes are universally conserved ribonucleoprotein complexes decoding the genetic information contained in messenger RNAs into proteins, their biogenesis show an intriguing degree of variability across the tree of life.
In this review we summarize our knowledge on the least understood ribosome biogenesis pathway: the archaeal one. Furthermore, we highlight some evolutionary conserved and divergent molecular features of making ribosomes across the tree of life.

Keywords: Archaea, ribosome, Ribosome biogenesis, ribosomal RNA, Ribosomal Proteins, RNA modifications

Received: 28 Mar 2021; Accepted: 14 May 2021.

Copyright: © 2021 Londei and Ferreira-Cerca. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Dr. Paola Londei, Department of Molecular Medicine, Faculty of Pharmacy and Medicine, Sapienza University of Rome, Roma, 00185, Lazio, Italy,
Dr. Sébastien Ferreira-Cerca, University of Regensburg, Regensburg, Germany,