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CORRECTION article

Front. Microbiol., 30 November 2021
Sec. Antimicrobials, Resistance and Chemotherapy
Volume 12 - 2021 | https://doi.org/10.3389/fmicb.2021.815909

Corrigendum: Fine-Tuning of Alkaline Residues on the Hydrophilic Face Provides a Non-toxic Cationic α-Helical Antimicrobial Peptide Against Antibiotic-Resistant ESKAPE Pathogens

This article is a correction to:

  1. Fine-Tuning of Alkaline Residues on the Hydrophilic Face Provides a Non-toxic Cationic α-Helical Antimicrobial Peptide Against Antibiotic-Resistant ESKAPE Pathogens

    1. Read original article
\nXudong Luo,Xudong Luo1,2Xiangdong Ye,Xiangdong Ye1,2Li Ding,Li Ding1,3Wen ZhuWen Zhu1Pengcheng YiPengcheng Yi1Zhiwen ZhaoZhiwen Zhao1Huanhuan GaoHuanhuan Gao1Zhan ShuZhan Shu1Shan LiShan Li1Ming SangMing Sang4Jue WangJue Wang1Weihua ZhongWeihua Zhong5Zongyun Chen, Zongyun Chen1,2*
  • 1Institute of Biomedicine and Hubei Key Laboratory of Embryonic Stem Cell Research, College of Basic Medicine, Hubei University of Medicine, Shiyan, China
  • 2Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Hubei University of Medicine, Shiyan, China
  • 3Department of Clinical Laboratory, Dongfeng Hospital, Hubei University of Medicine, Shiyan, China
  • 4Central Laboratory of Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Shiyan, China
  • 5Department of Rehabilitation Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, China

A Corrigendum on
Fine-Tuning of Alkaline Residues on the Hydrophilic Face Provides a Non-toxic Cationic α-Helical Antimicrobial Peptide Against Antibiotic-Resistant ESKAPE Pathogens

by Luo, X., Ye, X., Ding, L., Zhu, W., Yi, P., Zhao, Z., Gao, H., Shu, Z., Li, S., Sang, M., Wang, J., Zhong, W., and Chen, Z. (2021). Front. Microbiol. 12:684591. doi: 10.3389/fmicb.2021.684591

In the original article, the Figure 6A, which shows the survival curves of infected mice after treatment with BmKn2-7K, was placed mistakenly using the same image as Figure 5C, due to a mistake made inadvertently in the preparation of the revised manuscript. The corrected Figure 6 appears below.

FIGURE 6
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Figure 6. In vivo antimicrobial efficacy of BmKn2-7K. (A) Survival curves of infected mice after treatment with BmKn2-7K. Each cohort of ICR mice (n = 10) was infected with 5 × 107 cfu of S. aureus 4188 (or 6.25 × 107 cfu of A. baumannii 906) and cultured for 0.5 h to establish the lethal peritoneal infection model. Drug treatments were performed with a single dose of 20 (or 25) mg kg−1 body weight BmKn2-7K for the S. aureus 4188 (or A. baumannii 906) infected model, respectively. (B) Quantitative determination of bacterial loads in the peritoneal fluid of S. aureus infected ICR mice (n = 6). (C) Quantitative determination of bacterial loads in the peritoneal fluid of A. baumannii infected ICR mice (n = 6). The logarithm value of the number of viable bacteria from each mouse was plotted as individual dots, error bars represent the standard deviation from the mean within each cohort, **P < 0.01; and ***P < 0.001; ns represents “no significance.” The statistical significance between the groups was analyzed using one-way ANOVA followed by Tukey's post hoc test to correct for multiple comparisons.

The authors apologize for the error and state that the correction has not changed the description, interpretation, or the original conclusion of the manuscript. The original article has been updated.

Publisher's Note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: ESKAPE pathogens, antibiotic resistance, cationic α-helical antimicrobial peptide, hydrophilic face, lysine vs arginine, hemolytic activity, in vivo efficacy

Citation: Luo X, Ye X, Ding L, Zhu W, Yi P, Zhao Z, Gao H, Shu Z, Li S, Sang M, Wang J, Zhong W and Chen Z (2021) Corrigendum: Fine-Tuning of Alkaline Residues on the Hydrophilic Face Provides a Non-toxic Cationic α-Helical Antimicrobial Peptide Against Antibiotic-Resistant ESKAPE Pathogens. Front. Microbiol. 12:815909. doi: 10.3389/fmicb.2021.815909

Received: 16 November 2021; Accepted: 17 November 2021;
Published: 30 November 2021.

Approved by:

Frontiers Editorial Office, Frontiers Media SA, Switzerland

Copyright © 2021 Luo, Ye, Ding, Zhu, Yi, Zhao, Gao, Shu, Li, Sang, Wang, Zhong and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Zongyun Chen, chenzy2005@126.com

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.