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Correction ARTICLE

Front. Behav. Neurosci., 15 March 2016 | https://doi.org/10.3389/fnbeh.2016.00036

Corrigendum: Relationship Between L-DOPA-Induced Reduction in Motor and Exploratory Activity and Striatal Dopamine D2 Receptor Binding in the Rat

Susanne Nikolaus1*, Markus Beu1, Maria A. de Souza Silva2, Joseph P. Huston2, Hubertus Hautzel1, Claudia Mattern3,4, Christina Antke1 and Hans-Wilhelm Müller1
  • 1Clinic of Nuclear Medicine, University Hospital Düsseldorf, Düsseldorf, Germany
  • 2Center for Behavioural Neuroscience, Institute of Experimental Psychology, Heinrich-Heine University, Düsseldorf, Germany
  • 3M et P Pharma AG, Emmetten, Switzerland
  • 4Oceanographic Center, Nova Southeastern University, Fort Lauderdale, FL, USA

A corrigendum on
Relationship Between L-DOPA-Induced Reduction in Motor and Exploratory Activity and Striatal Dopamine D2 Receptor Binding in the Rat

by Nikolaus, S., Beu, M., de Souza Silva, M. A., Huston, J. P., Hautzel, H., Mattern, C., et al. (2016). Front. Behav. Neurosci. 9:352. doi: 10.3389/fnbeh.2015.00352

Line 13–19 on p. 5, right column, should read as follows:

“D2 receptor binding relative to baseline amounted to 21 ± 35% after 5 mg/kg L-DOPA/benserazide and to 19 ± 15% after 10 mg/kg L-DOPA/benserazide. Multiplication of percentual decreases by Kexo/Kendo yielded mean increases of synaptic DA by 213 ± 360% after 5 mg/kg L-DOPA/benserazide and by 199 ± 160% after 10 mg/kg L-DOPA/benserazide.”

Likewise, l. 9–14 on p. 13, right column, should read as follows:

“Changes of synaptic DA concentrations were estimated by multiplying the percentual alteration of exogenous ligand binding with the ratio of affinities (Kexo/Kendo), resulting in mean increases of DA by 213 ± 360% after 5 mg/kg and to 199 ± 160% after 10 mg/kg L-DOPA/benserazide.”

This error does not change the scientific conclusions of the article in any way.

Author Contributions

Writing of the manuscript: SN. Editing of the manuscript: MB, MASS, JPH, HH, CM, CA, and HWM.

Conflict of Interest Statement

The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Acknowledgments

MD was supported by a Heisenberg Fellowship SO 1032/5-1 and EU-FP7 (MC-ITN-“In-SENS”- ESR7 607616). JH was supported by “Deutsche Forschungsgemeinschaft” (Grant: DFG HU306/27-3).

Keywords: D2 receptor, [123I]IBZM, L-DOPA methylester, motor behavior, exploratory behavior, habituation, time-behavior curves, small animal SPECT

Citation: Nikolaus S, Beu M, de Souza Silva MA, Huston JP, Hautzel H, Mattern C, Antke C and Müller H-W (2016) Corrigendum: Relationship Between L-DOPA-Induced Reduction in Motor and Exploratory Activity and Striatal Dopamine D2 Receptor Binding in the Rat. Front. Behav. Neurosci. 10:36. doi: 10.3389/fnbeh.2016.00036

Received: 12 February 2016; Accepted: 16 February 2016;
Published: 15 March 2016.

Edited and reviewed by: Allan V. Kalueff, ZENEREI Institute, USA and Guangdong Ocean University, China, and St. Petersburg State University, Russia

Copyright © 2016 Nikolaus, Beu, de Souza Silva, Huston, Hautzel, Mattern, Antke and Müller. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Susanne Nikolaus, susanne.nikolaus@uni-duesseldorf.de