Corrigendum: Conditional Knockout of Cav2.1 Disrupts the Accuracy of Spatial Recognition of CA1 Place Cells and Spatial/Contextual Recognition Behavior
- 1Center for Neuroscience, Korea Institute of Science and Technology, Seoul, South Korea
- 2Neuroscience Program, Korea University of Science and Technology, Daejeon, South Korea
- 3Centre for Neuromedicine, Brain Science Institute, Korea Institute of Science and Technology, Seoul, South Korea
- 4VA Boston Healthcare System, Department of Neurology and Boston University Alzheimer's Disease Centre, Boston University School of Medicine, Boston, MA, United States
- 5Department of Neurophysiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
- 6Department of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata, Japan
by Jung, D., Hwang, Y. J., Ryu, H., Kano, M., Sakimura, K., and Cho, J. (2016). Front. Behav. Neurosci. 10:214. doi: 10.3389/fnbeh.2016.00214
In the original article, there were errors on citation. The statement on the mouse line from Mallmann's paper (Mallmann et al., 2013) was found to be irrelevant to our work and conclusion; thus the statement “Although a recent study circumvented the lethal phenotype by using the Cre-loxP system under the control of the NEX promoter to delete Cav2.1 in the neocortex, the mice still displayed substantial emotional impairments including anxiety and seizure. These affective changes observed in this transgenic mice line may have interfered with their performance in learning and memory tasks, therefore, results could be inconclusive in its attempt to identify the role of Cav2.1 in spatial learning and memory and hippocampal place cell activity” in the introduction section should be eliminated from this article.
In addition, the citation in the discussion section was misplaced at the end of statement to mislead information on specific subtype of calcium channels as following “Considering the previous studies, it is possible for dendritic Ca2+ influx via Cav2.1 to play a role in learning and memory in collaboration with NMDA channels by modulating bursting in that NMDA have been known to be involved in learning and memory both in vitro and in vivo studies (Cui et al., 2004; Moosmang et al., 2005; Place et al., 2012).” Therefore, the citation should be replaced to the appropriate place “Considering the previous studies (Cui et al., 2004; Moosmang et al., 2005; Place et al., 2012).”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.
The original article has been updated.
Conflict of Interest Statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Cui, Z., Wang, H., Tan, Y., Zaia, K. A., Zhang, S., and Tsien, J. Z. (2004). Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain. Neuron 41, 781–793. doi: 10.1016/S0896-6273(04)00072-8
Mallmann, R. T., Elgueta, C., Sleman, F., Castonguay, J., Wilmes, T., van den Maagdenberg, A., et al. (2013). Ablation of CaV2.1 voltage-gated Ca2+ channels in mouse forebrain generates multiple cognitive impairments. PLoS One 8:e78598. doi: 10.1371/journal.pone.0078598
Moosmang, S., Haider, N., Klugbauer, N., Adelsberger, H., Langwieser, N., Muller, J., et al. (2005). Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory. J Neurosci. 25, 9883–9892. doi: 10.1523/JNEUROSCI.1531-05.2005
Keywords: P/Q type calcium channels, burst, hippocampus, place cell, learning and memory
Citation: Jung D, Hwang YJ, Ryu H, Kano M, Sakimura K and Cho J (2017) Corrigendum: Conditional Knockout of Cav2.1 Disrupts the Accuracy of Spatial Recognition of CA1 Place Cells and Spatial/Contextual Recognition Behavior. Front. Behav. Neurosci. 11:242. doi: 10.3389/fnbeh.2017.00242
Received: 14 November 2017; Accepted: 23 November 2017;
Published: 08 December 2017.
Edited and reviewed by: Bruno Poucet, Centre National de la Recherche Scientifique (CNRS), France
Copyright © 2017 Jung, Hwang, Ryu, Kano, Sakimura and Cho. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Jeiwon Cho, firstname.lastname@example.org