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Correction ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Neurol. | doi: 10.3389/fneur.2019.00936

A Chinese Family With Adult-Onset Leigh-Like Syndrome Caused by the Heteroplasmic m.10191T>C Mutation in the Mitochondrial MTND3 Gene

 Tao-Ran Li1, 2, Qun Wang3, Mao-Mao Liu3 and  Rui-Juan Lv3*
  • 1Beijing Tiantan Hospital, Capital Medical University, China
  • 2Xuanwu Hospital, Capital Medical University, China
  • 3Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China

Incorrect Affiliation
In the published article, there was an error in affiliation “1”. Instead of “Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Beijing, China”, it should be “Department of Neurology, Beijing Tiantan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases, Beijing, China”. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Text Correction
In the original article, there was an error. There were two spelling mistakes in the article.
A correction has been made to DISCUSSION AND CONCLUSION, last sentence of Paragraph 8:
Recognition of the characteristics of these patients with the T10191C mutation will help us improve the clinical understanding of LS or Leigh-like syndrome.

In the original article, there was an omission. We did not get the heteroplasmy levels of the proband and her aunt from the gene sequencing company at the time of manuscript publication.
Through the follow-up research, we made the following addendum:
By detecting the proband’s and her aunt’s blood sample, we found the heteroplasmy level of the proband is 33.2% (forward percent) or 38.2% (reverse percent) respectively, the heteroplasmy level of her aunt is 4.4% (forward percent) or 4.8% (reverse percent) respectively.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Keywords: Leigh syndrome, Leigh-like syndrome, MELAS, MELAS-LS overlap syndrome, m.10191T>C mutation

Received: 31 May 2019; Accepted: 12 Aug 2019.

Copyright: © 2019 Li, Wang, Liu and Lv. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Mx. Rui-Juan Lv, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China, lvruijuan1981@126.com