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Towards an Understanding of Tinnitus Heterogeneity

Correction ARTICLE

Front. Neurosci., 08 May 2017 |

Corrigendum: Brain Metabolic Changes in Rats following Acoustic Trauma

Jun He1, Yejin Zhu1, Jiye Aa1, Paul F. Smith2,3,4,5, Dirk De Ridder3,4,5,6, Guangji Wang1 and Yiwen Zheng2,3,4,5*
  • 1Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China
  • 2Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand
  • 3Brain Health Research Centre, University of Otago, Dunedin, New Zealand
  • 4Brain Research New Zealand, Dunedin, New Zealand
  • 5Eisdell Moore Centre for Hearing and Balance Research, University of Auckland, Auckland, New Zealand
  • 6Department of Neurosurgery, Dunedin Medical School, University of Otago, Otago, New Zealand

A corrigendum on
Brain Metabolic Changes in Rats following Acoustic Trauma

by He, J., Zhu, Y., Aa, J., Smith, P. F., De Ridder, D., Wang, G., et al. (2017). Front. Neurosci. 11:148. doi: 10.3389/fnins.2017.00148

In the original article, the same graph was used for Figures 3A, 3E and 3I by mistake. The corrected Figure 3 appears below.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.


Figure 3. OPLS-DA and S-plot analysis comparing the OPLSDA scores between sham and acoustic trauma animals in different brain regions. Left panel, OPLSDA scores plots, red dots: Sham, purple dots: Acoustic trauma; Right panel, S-plots. (A,B) AC (Predictive component: R2X = 0.194, R2Y = 0.76, Q2 = 0.45; Orthogonal component 1: R2X = 0.446; All components: R2X (cum) = 0.64); (C,D) CB (Predictive component: R2X = 0.152, R2Y = 0.973, Q2 = 0.68; Orthogonal component 1: R2X = 0.364; All components: R2X (cum) = 0.927); (E,F) IC (Predictive component: R2X = 0.293, R2Y = 0.978, Q2 = 0.702; Orthogonal component 1: R2X = 0.417; All components: R2X (cum) = 0.905); (G,H) SC (Predictive component: R2X = 0.238, R2Y = 0.791, Q2 = 0.691; Orthogonal component: R2X = 0.562; All components: R2X (cum) = 0.8); (I,J) VNC(Predictive component: R2X = 0.403, R2Y = 0.779, Q2 = 0.445; Orthogonal component: R2X = 0.389; All components: R2X (cum) = 0.792). AC, auditory cortex; CB, cerebellum; IC, inferior colliculus; CN, cochlear nucleus; VCN, vestibular nucleus complex.

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Keywords: metabolomics, acoustic trauma, tinnitus, brain, rats

Citation: He J, Zhu Y, Aa J, Smith PF, De Ridder D, Wang G and Zheng Y (2017) Corrigendum: Brain Metabolic Changes in Rats following Acoustic Trauma. Front. Neurosci. 11:260. doi: 10.3389/fnins.2017.00260

Received: 01 April 2017; Accepted: 21 April 2017;
Published: 08 May 2017.

Edited and reviewed by: Winfried Schlee, University of Regensburg, Germany

Copyright © 2017 He, Zhu, Aa, Smith, De Ridder, Wang and Zheng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Yiwen Zheng,