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Front. Public Health | doi: 10.3389/fpubh.2018.00205

Health Economic Evaluations of Cancer in Brazil: a Systematic Review

 Alessandro G. Campolina1, 2, Tania Y. Yuba3,  Tassia C. Decimoni3,  Roseli Leandro3, Maria d. Diz2, Hillegonda M. Novaes3 and  Patricia C. Soarez3*
  • 1Instituto do Câncer do Estado de São Paulo, Brazil
  • 2Oncology, Instituto do Câncer do Estado de São Paulo, Brazil
  • 3Preventive Medicine, Faculdade de Medicina, Universidade de São Paulo, Brazil

Background: A large number of health economic evaluation (HEE) studies have been published in developed countries. However, Brazilian HEE literature in oncology has not been studied. Objective: To investigate whether the scientific literature has provided a set of HEE in oncology capable of supporting decision making in the Brazilian context. Methods: A systematic review was conducted to identify and characterize studies in this field. We searched multiple databases selecting partial and full HEE studies in oncology (1998-2013). Results: Fifty-five articles were reviewed, of these, 33 (60%) were full health economic evaluations. Type of cancers most frequently studied were: breast (38.2%), cervical (14.6%), lung (10.9%) and colorectal (9.1%). Procedures (47.3%) were the technologies most frequently evaluated. In terms of the intended purposes of the technologies, most (63.6%) were treatments. The majority of the incremental cost-effectiveness ratios (ICERs) reported have been below the cost-effectiveness threshold suggested by the World Health Organization (WHO). Conclusions: There has been an increase in the number of HEEs related to cancer in Brazil. These studies may support decision-making processes regarding the coverage of and reimbursement of healthcare technologies for cancer treatment in Brazil.

Keywords: Costs and Cost Analysis, Cost-Benefit Analysis, Health Care Costs, Neoplasms, Brazil

Received: 02 Apr 2018; Accepted: 04 Jul 2018.

Edited by:

Mihajlo (Michael) Jakovljevic, Faculty of Medical Sciences, University of Kragujevac, Serbia

Reviewed by:

Zoltán Vokó, Eötvös Loránd University, Hungary
Mary Codd, University College Dublin, Ireland
Julie Abimanyi-Ochom, Deakin University, Australia  

Copyright: © 2018 Campolina, Yuba, Decimoni, Leandro, Diz, Novaes and Soarez. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Prof. Patricia C. Soarez, Faculdade de Medicina, Universidade de São Paulo, Preventive Medicine, São Paulo, Brazil,