%A Koch,Bodil Cathrine %A Motta,Luca %A Wiinberg,Bo %A Westrup,Ulrik %A Kristensen,Annemarie Thuri %A Skerritt,Geoff %A Berendt,Mette %A Gredal,Hanne %D 2019 %J Frontiers in Veterinary Science %C %F %G English %K ischemic stroke,Infarction,Cerebrovascular Accident,Hemostatic parameters,D-dimer (DD),Hypercoagulability,Thromboelastography,TEG %Q %R 10.3389/fvets.2019.00255 %W %L %M %P %7 %8 2019-August-06 %9 Case Report %# %! Hemostatic parameters in canine stroke %* %< %T D-Dimer Concentrations and Thromboelastography in Five Dogs With Ischemic Stroke %U https://www.frontiersin.org/articles/10.3389/fvets.2019.00255 %V 6 %0 JOURNAL ARTICLE %@ 2297-1769 %X Ischemic stroke is a condition increasingly recognized in dogs; however, the number of publications on dogs with ischemic stroke is still limited and hemostatic parameters are infrequently reported. D-dimer levels have been shown to be elevated in people with acute ischemic stroke compared to a healthy control population and it has been proposed that a normal D-dimer can be used to exclude thromboembolism in dogs. In this case series, we report hemostatic parameters, including D-dimer and thromboelastography (TEG) along with clinical and imaging findings for five dogs diagnosed with ischemic stroke. All dogs had a normal D-dimer concentration on presentation. A hypercoagulable state was identified in two dogs based on the results of the TEG, and was suspected in the remaining three cases based on a shortened TEG clot reaction time. Based on the findings in the present cases, a D-dimer within the normal reference range does not seem an appropriate negative predictor for canine ischemic stroke. The demonstration of a possible hypercoagulable state, as identified by the TEG, is an interesting finding which should be explored further to help reveal predisposing hypercoagulable conditions in dogs with ischemic stroke.