Frontiers in Aging Neuroscience

Systematic Review

Published on 16 Jan 2026

The validity of visual and hearing impairment in predicting dementia and cognitive impairment in older adults: a systematic review and meta-analysis

Qingwen Gan
Yiling Yuan
Qianqian Hu
Yonghui Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1656686

1,114 views

Original Research

Published on 15 Jan 2026

Early and progressive retinal microglial changes in APPNL-F/NL-F mouse model of Alzheimer’s disease revealed by an automated image analysis software

Lidia Sánchez-Puebla
Inés López-Cuenca
Miguel A. Sánchez-Puebla
Ana Granados
Ana I. Ramírez
Juan Llorens
Takaomi C. Saido
Takashi Saito
Carmen Nieto-Vaquero
María A. Moro

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1712480

1,357 views

Original Research

Published on 15 Jan 2026

Polarity-dependent modulation of sleep oscillations and cortical excitability in aging

Buse Dikici
Robert Malinowski
Jan-Bernhard Kordaß
Klaus Obermayer
Julia Ladenbauer
Agnes Flöel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1704130

719 views

Review

Published on 15 Jan 2026

Effect of deep brain stimulation on dysphagia in Parkinson’s disease: mechanisms, evidence, and outlook

Jule Hofacker
Bahne H. Bahners
Cinja Huber
Christian J. Hartmann
Inga Claus
Sonja Suntrup-Krueger
Alfons Schnitzler
Tobias Warnecke
Bendix Labeit

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1734432

1,195 views

Original Research

Published on 15 Jan 2026

A cross-database bibliometric analysis of rapid eye movement sleep behavior disorder in Parkinson’s disease research

Shengjie Du
Xijiang Tian
Rui Ren
Luya Shi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1744493

1,097 views

Original Research

Published on 14 Jan 2026

Electroacupuncture alleviates Parkinson’s disease by targeting HDAC/SIRT-mediated deacetylation of 14-3-3

Zhao-Qin Wang
Han-Dan Zheng
Ling-Jie Li
Lu-Lu Cao
Lin Shen
Yu Qiao
Yi-Yi Chen
Lu-Yi Wu
Guo-Na Li
Huan-Gan Wu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1719326

993 views

Original Research

Published on 14 Jan 2026

The differential expression profiles of miRNA in serum-derived exosomes and its potential role in age-related hearing loss

Juhong Zhang
Haizhu Ma
Jing Ke
Ziyi Tang
Zhiji Chen
Guijun Yang
Li Yang
Jialin Guo
Xiaoqi Yan
Changxiu Peng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1694514

888 views

Original Research

Published on 14 Jan 2026

Cardiorespiratory fitness does not predict longitudinal changes in manual dexterity, cognition or corticospinal excitability in multiple sclerosis

Basel Mohamed
Sarah Duraid
Nick W. Bray
Arthur R. Chaves
Michelle Ploughman

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1628832

859 views

Original Research

Published on 13 Jan 2026

Influence of anesthetic agent and burst suppression on postoperative delirium in elderly patients: a prospective cohort study with automated EEG analysis

Maximilian Markus
Marc Dorenbeck
Vera Röhr
Sophie Leroy
Benjamin Blankertz
Emery N. Brown
Claudia Spies
Susanne Koch

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1743267

1,491 views

Original Research

Published on 13 Jan 2026

Correlation between blood biomarkers and post-stroke cognitive impairment

Xianjun Liu
Zhaoyang Lv
Zhihong Shi
Feng Liu
Hao Wu
Shuai Liu
Yong Ji

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1736338

863 views

Original Research

Published on 13 Jan 2026

The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease

Sonu Pahal
Akshatha Ganne
Meenakshisundaram Balasubramaniam
Sue T. Griffin
Robert J. Shmookler Reis
Srinivas Ayyadevara

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1713391

1,298 views

Original Research

Published on 13 Jan 2026

Machine learning-guided analysis of metabolomic alterations in Parkinson’s disease with comorbid symptoms

Ran Sun
Lin Wang
Yanli Wang
Jinghui Feng
Xingrao Wu
Jinbiao Li
Meng Wang
Wenxuan Chen
Hongping Lai
Hao Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1753016

759 views

Original Research

Published on 13 Jan 2026

Research trends and frontiers of astrocytes in cognitive impairment: a bibliometric analysis from 2015 to 2024

Zhilin Huang
Wanting Liu
Yating Zhang
BiXiang Zha
Ping Wang
Jun Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1708008

1,245 views

Original Research

Published on 13 Jan 2026

The olfactory functional network in the Alzheimer’s disease continuum: a resting state fMRI study

Daniela Ballotta
Claudia Casadio
Manuela Tondelli
Vanessa Zanelli
Francesco Ricci
Omar Carpentiero
Fausta Lui
Nicola Filippini
Annalisa Chiari
Maria Angela Molinari

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1744413

790 views

Editorial

Published on 12 Jan 2026

Editorial: The early detection of neurodegenerative diseases: an aging perspective

Paolo Abondio
Mirco Masi
Shaoyu Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1765664

735 views

Original Research

Published on 12 Jan 2026

Association of psychosis with cognitive impairment is mediated by amyloidopathy in cognitive impairment

Jung-Min Pyun
Sungjoo Han
Sang Won Park
Na Young Yeo
Young Ho Park
Sang Yun Kim
Young Chul Youn
Jae-Won Jang
and the Alzheimer’s Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1663120

837 views

Original Research

Published on 12 Jan 2026

Rewiring the aging brain: exergaming modulates brain complexity in older adults

Daghan Piskin
Helen Müller
Nina Skjæret-Maroni
Beatrix Vereijken
Jochen Baumeister

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1748274

899 views

Original Research

Published on 12 Jan 2026

Investigating age-related decline in sensorimotor control using robotic tasks

Laura Alvarez-Hidalgo
Ellie Edlmann
Gunnar Schmidtmann
Ian S. Howard

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1673516

648 views

Original Research

Published on 12 Jan 2026

The top 100 cited articles on artificial intelligence in Alzheimer’s disease and mild cognitive impairment: a bibliometric analysis

Zhi Tao
Rui Zhou
Yinggang Zheng
Lize Xiong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1605231

1,212 views

Review

Published on 12 Jan 2026

Beyond the auditory system: cognitive implications of age-related hearing loss

Fabiola Paciello
Anna Pisani
Anna Rita Fetoni
Claudio Grassi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1736579

1,126 views

Original Research

Published on 12 Jan 2026

Apolipoprotein A1 reduces blood–spinal cord barrier leakage, improves astrocytic coverage, and enhances motor neuron survival to restore the neurovascular unit in ALS mice

Svitlana Garbuzova-Davis
Larai Manora
Cesario V. Borlongan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1684694

910 views

Original Research

Published on 12 Jan 2026

Subclinical infection combined with surgery induced cognitive dysfunction: a novel adult mouse model for perioperative neurocognitive disorder

Chenchen Xia
Xiao Zhang
Wanbing Dai
Yizhe Zhang
Ye Liu
Xiangyang Cheng
Yeke Zhu
Lili Huang
Minghao Tang
Yongxing Yao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1691681

868 views

Original Research

Published on 12 Jan 2026

A 24-week multi-component exercise program improves cognition and body composition in older adults with mild cognitive impairment: a randomized controlled trial

Danming Xu
Xiaochu Wu
Junming Dai
Qing Li
Zhi Wang
Yimin Huang
Yu Zhang
Junjie Cao
Bingxue Li
Yirong Dong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1711554

898 views

7,808 Publications

volumes

Volume 17 - 2025

The validity of visual and hearing impairment in predicting dementia and cognitive impairment in older adults: a systematic review and meta-analysis

Early and progressive retinal microglial changes in APPNL-F/NL-F mouse model of Alzheimer’s disease revealed by an automated image analysis software

Polarity-dependent modulation of sleep oscillations and cortical excitability in aging

Effect of deep brain stimulation on dysphagia in Parkinson’s disease: mechanisms, evidence, and outlook

A cross-database bibliometric analysis of rapid eye movement sleep behavior disorder in Parkinson’s disease research

Electroacupuncture alleviates Parkinson’s disease by targeting HDAC/SIRT-mediated deacetylation of 14-3-3

The differential expression profiles of miRNA in serum-derived exosomes and its potential role in age-related hearing loss

Cardiorespiratory fitness does not predict longitudinal changes in manual dexterity, cognition or corticospinal excitability in multiple sclerosis

Influence of anesthetic agent and burst suppression on postoperative delirium in elderly patients: a prospective cohort study with automated EEG analysis

Correlation between blood biomarkers and post-stroke cognitive impairment

The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease

Machine learning-guided analysis of metabolomic alterations in Parkinson’s disease with comorbid symptoms

Research trends and frontiers of astrocytes in cognitive impairment: a bibliometric analysis from 2015 to 2024

The olfactory functional network in the Alzheimer’s disease continuum: a resting state fMRI study

Editorial: The early detection of neurodegenerative diseases: an aging perspective

Association of psychosis with cognitive impairment is mediated by amyloidopathy in cognitive impairment

Rewiring the aging brain: exergaming modulates brain complexity in older adults

Investigating age-related decline in sensorimotor control using robotic tasks

The top 100 cited articles on artificial intelligence in Alzheimer’s disease and mild cognitive impairment: a bibliometric analysis

Beyond the auditory system: cognitive implications of age-related hearing loss

Apolipoprotein A1 reduces blood–spinal cord barrier leakage, improves astrocytic coverage, and enhances motor neuron survival to restore the neurovascular unit in ALS mice

Subclinical infection combined with surgery induced cognitive dysfunction: a novel adult mouse model for perioperative neurocognitive disorder

A 24-week multi-component exercise program improves cognition and body composition in older adults with mild cognitive impairment: a randomized controlled trial

Volume 18 - 2026

Research on Alzheimer's Disease MRI Image Classification Based on Spatial Attention Mechanism