Frontiers in Aging

Original Research

Published on 06 Jun 2025

The curvilinear associations between Life’s Crucial 9 and frailty: cross-sectional study of NHANES 2003 - 2023

in Interventions in Aging

Bo Wang
Chunqi Jiang
Ning Wang
Yinuo Qu
Jun Wang
Guang Zhao
Xin Zhang

Frontiers in Aging

doi 10.3389/fragi.2025.1528338

732 views

Mini Review

Accepted on 05 Jun 2025

Rapamycin for longevity: the pros, the cons, and future perspectives

in Aging, Metabolism and Redox Biology

Kelley Marie Roark
Philip Henry Iffland II

Frontiers in Aging

doi 10.3389/fragi.2025.1628187

315 views

Original Research

Accepted on 05 Jun 2025

Possibility of Screening for Mild Cognitive Impairment via an Eye Tracking-Based Cognitive Scale

in Healthy Longevity

Naoki Kodama
Sou Takahashi
Masazumi Tsuji
Yuji Kawase
Satoshi Naruse
Katsuya Urakami

Frontiers in Aging

doi 10.3389/fragi.2025.1532550

Original Research

Published on 04 Jun 2025

Membrane transporter progressive ankylosis protein homologue (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation, and ageing

in Cellular Senescence

Emma Naomi James
Muy-Teck Teh
Yufeng Li
Christine Wagner-Bock
Zahra Falah Al-Khateeb
Lee Peng Karen-Ng
Terry Roberts
Linnea Synchyshyn
Amy Lewis
Ana O’Loghlen

Frontiers in Aging

doi 10.3389/fragi.2025.1583288

610 views

Mini Review

Accepted on 03 Jun 2025

MOLECULAR CONSTRAINTS OF SARCOPENIA IN THE AGEING MUSCLE

in Musculoskeletal Aging

Sarah Damanti
Eleonora Senini
Rebecca De Lorenzo
Aurora Merolla
Simona Santoro
Costanza Festorazzi
Marco Messina
Giordano Vitali
Clara Sciorati
Angelo A. Manfredi

Frontiers in Aging

doi 10.3389/fragi.2025.1588014

114 views

Methods

Accepted on 03 Jun 2025

Prevention in nursing care: A study protocol of a cluster-randomized controlled trial on the effects of physical exercise and environmental interventions on physical activity behavior and physical functioning in nursing home residents (PROGRESS study)

in Interventions in Aging

Vera Belkin
Tanja I Janssen
Julian Rudisch
Bettina Wollesen
Claudia Voelcker-Rehage

Frontiers in Aging

doi 10.3389/fragi.2025.1466315

108 views

Systematic Review

Accepted on 03 Jun 2025

Mapping the global research landscape and trends of older people living alone: A Bibliometric Analysis

in Interventions in Aging

Guang-Wei Zhang
Yu-Dan Wu
Jia-Xin Dong
Fu-Min Yu
Zhe-Hao Dong
Wei Ma
Yue Cai
Yu-Qing Cai
Yang Mu
Xiang Cui

Frontiers in Aging

doi 10.3389/fragi.2025.1524673

Original Research

Accepted on 02 Jun 2025

Intrinsic capacity, functional and psychosocial aspects of older adults participating in a multicomponent physical exercise program

in Healthy Longevity

Sarah Felipe
Clarissa Biehl Printes
Fabiane de Oliveira Brauner
Douglas Kazutoshi Sato
Rafael Reimann Baptista

Frontiers in Aging

doi 10.3389/fragi.2025.1562383

113 views

Review

Published on 02 Jun 2025

Enhancing active aging through exercise: a comparative study of high-intensity interval training and continuous aerobic training benefits

in Healthy Longevity

Federico Zoila
Francesca Martina Filannino
Maria Antonietta Panaro
Italo Sannicandro
Antonia Cianciulli
Chiara Porro

Frontiers in Aging

doi 10.3389/fragi.2025.1493827

1,536 views

Original Research

Published on 02 Jun 2025

Right hemisphere engagement in language abilities in older adults: indication of compensation rather than decline

in Healthy Longevity

Daniel Solomons
Maria Rodriguez-Fernandez
Francisco Mery-Muñoz
Leonardo Arraño-Carrasco
David Toloza-Ramirez
Francisco Sahli-Costabal
Carolina Mendez-Orellana

Frontiers in Aging

doi 10.3389/fragi.2025.1458692

1,679 views

Original Research

Accepted on 30 May 2025

Regulation of Enzymes of De Novo Lipid Metabolism by Chaperone-Mediated Autophagy: Effects of the Lifespan-Extending MEK1 Inhibitor Trametinib

in Interventions in Aging

Jiexian Chen
Josh Berg
Calvin M Burns
Hanyi Jia
Xinna Li
Richard A Miller
S. Joseph Endicott
Gonzalo Garcia

Frontiers in Aging

doi 10.3389/fragi.2025.1621808

235 views

Brief Research Report

Published on 30 May 2025

Oropharyngeal detection of specific gut-derived Enterobacterales is associated with increased respiratory infection risk in older adults

in Healthy Longevity

Sophie J. Miller
Frank Zhang
Steven L. Taylor
Andrew P. Shoubridge
Erin Flynn
Egi Vasil
Richard J. Woodman
Lito E. Papanicolas
Geraint B. Rogers

Frontiers in Aging

doi 10.3389/fragi.2025.1566034

1,662 views

Brief Research Report

Published on 30 May 2025

Convergent and predictive validity of the activities-specific balance confidence scales and balance recovery confidence scale, with regard to the falls efficacy scale-international: a cross-sectional study

in Interventions in Aging

Hazel Xu Teng Ting
Jiaying Ho
Peck Hoon Ong
William R. Young
Shawn Leng Hsien Soh

Frontiers in Aging

doi 10.3389/fragi.2025.1330612

393 views

Original Research

Published on 30 May 2025

Ovarian ROS-dependent IgG accumulation precedes lipofuscin deposition and follicular decline: comparative insights from the bitch and mouse models of ovarian aging

in Aging, Metabolism and Redox Biology

Luís Montenegro
Natália Rigos
Catarina Brandão
Anabela Pinto
Inês Borges
Luís Cardoso
Hugo Carvalho
Henrique Almeida
Ana Martins-Bessa
Elisabete Silva

Frontiers in Aging

doi 10.3389/fragi.2025.1567909

649 views

Original Research

Published on 30 May 2025

Research on intrinsic capacity as a predictor of falls and disability in community-dwelling elderly

in Healthy Longevity

Aihong Liu
Yanjie You
Yumei Wang
Ling Li
Jinrong Yuan

Frontiers in Aging

doi 10.3389/fragi.2025.1589369

1,789 views

Original Research

Published on 30 May 2025

Sex differences in the association between Life’s Essential 8 and serum anti-aging Klotho protein levels: a cross-sectional analysis in middle-aged to older adults

in Healthy Longevity

Jing Zeng
Tingting Zhang
Yan Yang
Jinjing Wang
Xiaojing Fan
Qiaomin Wang
Xuan Wang
Haoxian Tang
Yi Fang

Frontiers in Aging

doi 10.3389/fragi.2025.1458571

1,587 views