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ORIGINAL RESEARCH article

Front. Bioeng. Biotechnol.

Sec. Tissue Engineering and Regenerative Medicine

This article is part of the Research TopicCraniomaxillofacial Reconstruction: from Bench to BedsideView all 4 articles

Can Titanium Miniplates Provide Superior Fixation Compared to Reconstruction Plates in Mandibular Repair with Iliac Crest Flaps? : A Retrospective Study

Provisionally accepted
Tianfu  WuTianfu Wu1*Wen-qing  LinWen-qing Lin2Da  LiuDa Liu2Renbin  ZhouRenbin Zhou1Hao  LinHao Lin1Bang  ZengBang Zeng1Jun  JiaJun Jia1Yifang  ZhaoYifang Zhao1Bing  LiuBing Liu1
  • 1Wuhan University, Wuhan, China
  • 2Stomatologic Hospital of Xiamen Medical College, Xiamen, China

The final, formatted version of the article will be published soon.

This study retrospectively analyzed 112 patients who underwent mandibular reconstruction with vascularized iliac crest flaps using different fixation strategies in routine clinical practice. Under comparable defect lengths and heights, reconstruction using mini plates was associated with the shortest operative time (p < 0.001), while postoperative drainage duration showed no significant difference among groups (p = 0.958). The number of iliac bone segments varied significantly among fixation methods: reconstruction plates (alone or combined with mini plates) were predominantly applied in multi-segmental reconstructions, whereas mini plates were mainly used for single-segmental repairs. Postoperative quality of life was evaluated using the University of Washington Quality of Life Questionnaire (UW-QoL). Although the fixation methods were selected according to defect complexity and surgical requirements, all approaches achieved satisfactory outcomes, and no significant difference in overall quality-of-life scores was observed among the three groups (p = 0.354). However, a significant difference was observed in the "Swallowing" domain, with patients in the mini plate group reporting better swallowing function (p = 0.009).

Keywords: Titanium miniplate, Reconstruction plate, Mandibular reconstruction, vascularized iliac crest flap, complication, Fixation method, Mini plate, Quality of Life

Received: 19 Aug 2025; Accepted: 17 Nov 2025.

Copyright: © 2025 Wu, Lin, Liu, Zhou, Lin, Zeng, Jia, Zhao and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Tianfu Wu, wutianfu@whu.edu.cn

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