ORIGINAL RESEARCH article
Front. Bioeng. Biotechnol.
Sec. Biofabrication
This article is part of the Research TopicCraniomaxillofacial Reconstruction: from Bench to BedsideView all 8 articles
In vitro evaluation of a self-positioning individualized titanium mesh for improved accuracy in guided bone regeneration
Provisionally accepted
- 1Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital Department of Radiotherapy, Shanghai, China
- 2Hangzhou Normal University Hangzhou Department of Medicine, Hangzhou, China
- 3West Branch of Hangzhou Stomatology Hospital, Hangzhou, Zhejiang, China 310012, Hangzhou, China
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Introduction: Adequate bone volume and contour are essential for successful implant placement. This study evaluated the accuracy of a novel self-positioning three-dimensional printed individualized titanium mesh (3D-PITM) in guided bone regeneration (GBR). Methods: Ten identical maxillary phantoms with standardized defects were divided into an experimental self-positioning 3D-PITM group and a conventional 3D-PITM group. Pre-and postoperative CBCT scans were obtained for 3D reconstruction and superimposition. Deviations in augmented contours, screw placement, volumetric accuracy, and 2D cross-sectional augmentation were analyzed. Results: The self-positioning group showed significantly reduced deviation in augmentation contours (0.82 ± 0.07 mm vs. 1.02 ± 0.13 mm, P = 0.003), improved screw placement accuracy (0.10 ± 0.13 mm vs. 0.65 ± 0.32 mm, P = 0.026), and lower volumetric discrepancies. Two-dimensional evaluation confirmed greater vertical and horizontal accuracy in bone augmentation (P = 0.021, P = 0.018). Conclusion: The self-positioning 3D-PITM achieved more accurate installation and predictable bone augmentation in vitro, suggesting potential clinical advantages for implant-supported rehabilitation.
Keywords: Dental implantology, Dimensional accuracy, Guided bone regeneration (GBR), in vitroevaluation, Individualized titanium mesh, self-positioning design
Received: 04 Oct 2025; Accepted: 12 Jan 2026.
Copyright: © 2026 Zhang, Xu, Tao, Zhang, Chen and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Dedong Vincent Yu
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