Frontiers in Bioinformatics

Original Research

Accepted on 23 Jun 2025

Understanding the selectivity in silico of colistin and daptomycin toward Gram-negative and Gram-positive bacteria, respectively, from the interaction with membrane phospholipids

Jose Oñate
Yamil Liscano
Yesid Aristizabal

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1569480

201 views

Editorial

Published on 19 Jun 2025

Editorial: Expert opinions in genomic analysis

João C. Setubal
Alberto Paccanaro

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1641083

414 views

Brief Research Report

Published on 19 Jun 2025

ICARus: a pipeline to extract robust gene expression signatures from transcriptome datasets

Zhaorong Li
Juan I. Fuxman Bass

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1604418

591 views

Methods

Published on 18 Jun 2025

Enhancing genomic prediction in Arabidopsis thaliana with optimized SNP subset by leveraging gene ontology priors and bin-based combinatorial optimization

Qingfang Ba
Heng Zhou
Zheming Yuan
Zhijun Dai

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1607119

452 views

Original Research

Published on 18 Jun 2025

Temporal GeneTerrain: advancing precision medicine through dynamic gene expression visualization

Ehsan Saghapour
Rahul Sharma
Delower Hossain
Kevin Song
Zhandos Sembay
Jake Y. Chen

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1602850

1,033 views

Original Research

Published on 17 Jun 2025

Utility of regional STR marker variations in Tunisian and sub-Saharan populations: insights into forensic and population genetics

Asma Attaoui
Hajer Foddha
Houcemeddine Othman
Hassen Ben Abdennebi
Amel Haj Khelil

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1550730

557 views

Original Research

Published on 11 Jun 2025

Optimization of clustering parameters for single-cell RNA analysis using intrinsic goodness metrics

Nicolina Sciaraffa
Antonino Gagliano
Luigi Augugliaro
Claudia Coronnello

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1562410

897 views

Original Research

Published on 09 Jun 2025

TICTAC: target illumination clinical trial analytics with cheminformatics

Jeremiah I. Abok
Jeremy S. Edwards
Jeremy J. Yang

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1579865

833 views

Brief Research Report

Published on 06 Jun 2025

Interactive visualization of large molecular systems with VTX: example with a minimal whole-cell model

Maxime Maria
Valentin Guillaume
Simon Guionnière
Nicolas Dacquay
Cyprien Plateau–Holleville
Vincent Larroque
Jean Lardé
Yassine Naimi
Jean-Philip Piquemal
Guillaume Levieux

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1588661

1,314 views

Technology and Code

Published on 06 Jun 2025

DeepPredict: a state-of-the-art web server for protein secondary structure and relative solvent accessibility prediction

Wafa Alanazi
Di Meng
Gianluca Pollastri

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1607402

999 views

Original Research

Accepted on 30 May 2025

Design of cross-reactive antigens with machine learning and high-throughput experimental evaluation

Chelsy Chesterman
Thomas Desautels
Luz-Jeannette Sierra
Kathryn Arrildt
Adam Zemla
Edmond Lau
Shivshankar Sundaram
Jason Laliberte
Lynn Chen
Aaron Ruby

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1580967

287 views

Perspective

Published on 30 May 2025

Trail-blazing and keeping pace: building, retaining and expanding image analysis expertise

David Kirchenbuechler
Mariana De Niz
Constadina Arvanitis

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1613866

822 views

Original Research

Published on 29 May 2025

In silico analysis of Triphala-derived polyphenols as inhibitors of TIR–TIR homodimerization in the inflammatory pathway

Durgadevi Rajendran
Nalini Easwaran

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1565700

1,226 views

Original Research

Published on 29 May 2025

Bridging the gap between hepatocellular carcinoma management guidelines and personalised medicine: a Bayesian network study

Yi-Chun Wang
Daniel Bulte
Michael Brady

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1574797

782 views

Brief Research Report

Published on 26 May 2025

Quality over quantity: how to get the best results when using docking for repurposing

Lenin Domínguez-Ramírez
Maricruz Anaya-Ruiz
Paulina Cortés-Hernández

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1536504

1,298 views

Original Research

Published on 26 May 2025

CytoLNCpred-a computational method for predicting cytoplasm associated long non-coding RNAs in 15 cell-lines

Shubham Choudhury
Naman Kumar Mehta
Gajendra P. S. Raghava

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1585794

928 views

474 Publications

Volume 5 - 2025

Understanding the selectivity in silico of colistin and daptomycin toward Gram-negative and Gram-positive bacteria, respectively, from the interaction with membrane phospholipids

Editorial: Expert opinions in genomic analysis

ICARus: a pipeline to extract robust gene expression signatures from transcriptome datasets

Enhancing genomic prediction in Arabidopsis thaliana with optimized SNP subset by leveraging gene ontology priors and bin-based combinatorial optimization

Temporal GeneTerrain: advancing precision medicine through dynamic gene expression visualization

Utility of regional STR marker variations in Tunisian and sub-Saharan populations: insights into forensic and population genetics

Optimization of clustering parameters for single-cell RNA analysis using intrinsic goodness metrics

TICTAC: target illumination clinical trial analytics with cheminformatics

Interactive visualization of large molecular systems with VTX: example with a minimal whole-cell model

DeepPredict: a state-of-the-art web server for protein secondary structure and relative solvent accessibility prediction

Design of cross-reactive antigens with machine learning and high-throughput experimental evaluation

Trail-blazing and keeping pace: building, retaining and expanding image analysis expertise

In silico analysis of Triphala-derived polyphenols as inhibitors of TIR–TIR homodimerization in the inflammatory pathway

Bridging the gap between hepatocellular carcinoma management guidelines and personalised medicine: a Bayesian network study

Quality over quantity: how to get the best results when using docking for repurposing

CytoLNCpred-a computational method for predicting cytoplasm associated long non-coding RNAs in 15 cell-lines