In the published article, there was an error in Figure 1 as published. The SNP screening threshold was incorrectly written as P < 1 × 10−8. The correct threshold is P < 5 × 10−8. The corrected Figure 1 and it's caption appears below.
Figure 1
(A) The basic assumptions of MR and (B) study design. SNP, single nucleotide polymorphisms; ICP, intrahepatic cholestasis of pregnancy; IVW, inverse variance weighted; WM, weighted median; CVD, cardiovascular disease; HTN, hypertension; CAD, coronary artery disease; GWAS, genome-wide association studies; IEU, integrative epidemiology unit open GWAS project.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
In the published article, there was an error. A prerequisite for the exclusion of outlier SNPs is missing before the description of the results of the sensitivity analyses.
A correction has been made to Results, 3.1 Causal effect between ICP and CVD (CAD, HTN) via TSMR. This sentence previously stated:
“The robustness of the results was assessed through Cochran's Q test, the MR-Egger intercept test and MR-PRESSO, as detailed in Supplementary Material Table S3.”
The corrected sentence appears below:
“After removing outlier SNP, the causal relationship between ICP and CVD still remained. The robustness of the results after removing outlier SNP was assessed through Cochran's Q test, the MR-Egger intercept test and MR-PRESSO, as detailed in Supplementary Material Table S3.”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
In the published article, there was an error in Supplementary Table 3. The results of the sensitivity analyses in the original Supplementary Table 3 were incorrectly calculated due to incomplete data extraction and exclusion of outlier SNP values; the revised results are shown in the corrected Supplementary Table 3. The correct material statement appears below.
| Exposure-outcome | Q | Q p-value | MR-Egger interpreter | MR-Egger interpreter p-value | MR-PRESSO |
|---|---|---|---|---|---|
| ICP-CVD | 9.525 | 0.146 | 0.019 | 0.377 | 0.244 |
| ICP-HTN | 15.110 | 0.035 | 0.000 | 0.931 | 0.068 |
| ICP-CAD | 0.001 | 0.977 | – | – | – |
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Statements
Publisher’s note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Summary
Keywords
intrahepatic cholestasis of pregnancy, lipid, cardiovascular disease, Mendelian randomization, GWAS
Citation
Cui J, Zhai Q, Chen M and Yang Z (2024) Corrigendum: Genetically predicted lipids mediate the association between intrahepatic cholestasis of pregnancy and cardiovascular disease. Front. Cardiovasc. Med. 11:1439868. doi: 10.3389/fcvm.2024.1439868
Received
28 May 2024
Accepted
05 July 2024
Published
18 July 2024
Volume
11 - 2024
Edited and reviewed by
Chieko Mineo, University of Texas Southwestern Medical Center, United States
Updates
Copyright
© 2024 Cui, Zhai, Chen and Yang.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Mengjie Chen chenmengjie@hospital.cqmu.edu.cn Zhu Yang yangzhu@hospital.cqmu.edu.cn
†These authors have contributed equally to this work and share first authorship
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.