CASE REPORT article

Front. Cardiovasc. Med.

Sec. Cardio-Oncology

Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1455947

This article is part of the Research TopicCase Reports in Cardio-Oncology: 2024View all 13 articles

Multiple Cardiac Papillary Fibroelastomas: A Case Report and Review of the Literature

Provisionally accepted
  • Mayo Clinic Florida, Jacksonville, United States

The final, formatted version of the article will be published soon.

Cardiac papillary fibroelastomas (PFEs) are the most common benign cardiac tumors and are typically solitary. PFEs affecting both sides of the heart are exceptionally rare, with only four cases reported in the literature. Herein we report a case of a 63-year-old male presenting with signs and symptoms of embolic strokes and embolism to coronary arteries. Echocardiogram shows multiple masses on both the mitral and tricuspid valve leaflets. Because of the risk of embolism, he underwent successful valve-sparing surgical resection without complications. Follow-up echocardiogram at six months showed no recurrence and competence of both mitral and tricuspid valves with minimal regurgitation.

Keywords: Cardiac papillary fibroelastomas, cardiac tumor, Valvular abnormalities, cardiac surgery, management of heart tumors

Received: 27 Jun 2024; Accepted: 07 May 2025.

Copyright: © 2025 Ali, Alomari, El-Sayed Ahmed, MD, MS, Garg, Pham and Pham. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Mohammad Alomari, Mayo Clinic Florida, Jacksonville, United States
Si Pham, Mayo Clinic Florida, Jacksonville, United States

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