ORIGINAL RESEARCH article

Front. Cardiovasc. Med.

Sec. Coronary Artery Disease

Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1484401

Impact of cardiac rehabilitation and treatment compliance after ST-segment elevation myocardial infarction (STEMI) in France, the STOP SCA+ study

Provisionally accepted
Emeline LaurentEmeline Laurent1,2Lucile GodillonLucile Godillon2Marc-Florent TassiMarc-Florent Tassi2Pierre MarcolletPierre Marcollet3Stéphan ChassaingStéphan Chassaing4Marie DecomisMarie Decomis5Julien BezinJulien Bezin6Christophe LaureChristophe Laure7Denis AngoulvantDenis Angoulvant1,8Grégoire RangeGrégoire Range7Leslie GRAMMATICO-GUILLONLeslie GRAMMATICO-GUILLON1,2*
  • 1Faculté de Médecine, Université de Tours, Tours, France
  • 2E^pidemiologie des données cliniques CVL, Pole santé publique et prévention, CHU de Tours, France, Tours, France
  • 3France PCI, Bourges, France
  • 4France PCI, Private Hospital NCT+, France
  • 5France PCI, private hospital Oreliance, Orléans, France
  • 6Univ. Bordeaux, INSERM, BPH, team AHeaD, U1219, CHU de Bordeaux, Clinical Pharmacology Unit, Bordeaux, France
  • 7France PCI, Chartres, France
  • 8Service de cardiologie, CHU Tours, Tours, France

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Introduction: Acute ST elevation myocardial infarction (STEMI) is a frequent and serious presentation of acute coronary syndrome. The STOP SCA+ study aimed to i) describe oneyear compliance to secondary prevention cardiac tri-therapy, and ii) identify factors associated with negative outcomes one year after STEMI, particularly the impact of compliance and rehabilitation care.Methods: Patients>18 years old hospitalized for STEMI in five interventional cardiac centers with the same cardiac registry in one French region (2.5 million inhabitants), between 2014 and 2018, were included. After a probabilistic matching with the National Health Insurance database (SNDS, 96% matching), compliance for cardiac tri-therapy was studied: aspirin, P2Y12 inhibitor, statin. Factors associated with poor outcomes (ischaemic complications, death) were analyzed using Cox modelling and those for the compliance by logistic regression.rehabilitation. Compliance part in patient health outcome will need further modelling to accurately study its impact. Matching clinical and medico-administrative databases proved to be relevant for assessing outcomes at a large scale.

Keywords: MI: myocardial infarction, cardiac rehabiliation, Compliance, Outcome, Probabilistic matching

Received: 26 Sep 2024; Accepted: 22 May 2025.

Copyright: © 2025 Laurent, Godillon, Tassi, Marcollet, Chassaing, Decomis, Bezin, Laure, Angoulvant, Range and GRAMMATICO-GUILLON. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Leslie GRAMMATICO-GUILLON, Faculté de Médecine, Université de Tours, Tours, France

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Supplementary Material