BRIEF RESEARCH REPORT article
Front. Cardiovasc. Med.
Sec. Cardiovascular Epidemiology and Prevention
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1577793
This article is part of the Research TopicEnvironmental Determinants of Cardiovascular Health: Interactions with Lifestyle and Socioeconomic FactorsView all 4 articles
Cardiovascular disease in North African Women: Insights from the Women CardioVascular Disease Middle East African (MEA-WCVD) Registry
Provisionally accepted
Salma Charfeddine1*
Leila Abid1
Sarra Chenik2Aymen Ghrab1Oussama Haddar1Iheb Ben Krayen3Selim Boudiche4Haithem Touati5Oumaima Ayedi1Mohamed Amine Ammar6Manel Ben Halima4Houssem Ben Ayed2Asma Brahim4Faten ElAyech7Houssem Thabet8*Houaida Mahfoudhi2Taha Yessine Jabloun2Yasmine Ayadi1Alaeddine Ayadi9Ghassen Romdhani10Hassen Gargouri1Oumayma Zidi11Mohamed Ali Guedri12Rami Tlili9Bechir Trabelsi10Selim Hammami1Rim Othmen10Saoussen Antit13Syrine Saidane12Sirine Dardour10Skander Iddir10Elmahdi Kharrat10Anis Cheikhrouhou1Mohamed Derwich1Amal Mrabet10Taha Lassoued3Emna Rekik1Sahar Gmiha1Niez Laribi1Hakim Lamine10Zied Triki9Samir Ayari6Fatma Boujelbene14Essia Boughzela15Hajer Rekik14Ines Ben Ameur14Syrine Abid15Khalil Oueghlani16Abddayem Haggui2Afef Ben Halima11Wejdene Ouechtati7Emna Bennour11Rania Hammami1Mariem Jabeur1Ihsen Zairi10Mariem Drissa9Faouzi Addad15Sami Milouchi3Mohamed Sami Mourali4Hedi Ben Slima6Leila Bezdah7Elyes Neffati8Youssef Ben Ameur9Sondos Kraiem10Salem Kachboura11Ikram Kammoun11Lilia Zakhama13Hassen lbn Hadj Amor17Khaldoun Ben Hamda18Yosra Messoudi19Nejah Ben Hlima19Rana Dahmani20Habib Gamra21Zied Ibn Elhadj22Hichem Denguir23Chayma Ghorbel24Nizar Mechri25Samia Ernez Hajri26Alexandre Mebazaa27
Fedi Ben Dhaou28Maroua Trigui28Wafa Fehri2Salem Abdessalem29- 1Cardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia
- 2Cardiology Department, Military University Hospital, Tunis, Tunisia
- 3Cardiology Department, Habib Bourguiba University Hospital, Medenine, Tunisia
- 4Cardiology Department, La Rabta University Hospital, Tunis, Tunisia
- 5Cardiology Department, Habib Bourguiba University Hospital, Sfax, Tunisia
- 6Cardiology Department, Menzel Bourguiba university hospital, Bizerte, Tunisia
- 7Cardiology Department, Charles Nicolle university hospital, Tunis, Tunisia
- 8Cardiology Department, Sahloul University Hospital, Sousse, Tunisia
- 9Cardiology Department, Mongi Slim La Marsa University Hospital, Tunis, Tunisia
- 10Cardiology Department, Habib Thameur University Hospital, Tunis, Tunisia
- 11Cardiology Department, Abderrahman Mami university hospital, Ariana, Tunisia
- 12Habib Thameur University Hospital, Tunis, Tunisia
- 13Cardiology Department, FSI La Marsa university hospital, Tunis, Tunisia
- 14Private cardiologist, Sfax, Tunisia
- 15Private cardiologist, Tunis, Tunisia
- 16Cardiology Department, Djerba hospital, Medenine, Tunisia
- 17Cardiology Department, Taher Sfar university hospital, Mahdia, Tunisia
- 18Cardiology Department, Fattouma Bourguiba University Hospital, Monastir, Tunisia
- 19Cardiology Department, Ibn El Jazzar university hospital, Kairouan, Tunisia
- 20Cardiology Department, Military University Hospital, Bizerte, Tunisia
- 21Cardiology Department A, Fattouma Bourguiba University Hospital, Monastir, Tunisia
- 22Cardiology Department, Taher Maamouri university hospital, Nabeul, Tunisia
- 23Cardiology Department, Gabes University Hospital, Gabes, Tunisia
- 24Cardiology Department, Kasserine hospital, Kasserine, Tunisia
- 25Cardiology Department, Tatouine hospital, Tatouine, Tunisia
- 26Cardiology Department, Farhat Hached university hospital, Sousse, Tunisia
- 27Department of Anesthesia and Critical Care, Hôpital Lariboisière, Paris, France
- 28Hygiene Department, Habib Bourguiba University Hospital, Sfax, Tunisia
- 29Cardiology Department, Clinic Pasteur, Tunis, Tunisia
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Numerous studies have uncovered substantial disparities in cardiovascular health between men and women, as well as among different subsets of women (1-4) . Despite this, a lack of data exists regarding the distinct features of cardiovascular disease in women within the Middle East North Africa (MENA) Region (5,6). This research gap has led to the underdiagnosis, undertreatment, and under-research of prevalent cardiovascular diseases (CVD), such as coronary heart disease (CHD) including ST-elevation myocardial infarction (STEMI), non ST-elevation myocardial infarction (NSTEMI) and chronic coronary syndrome (CCS), heart failure (HF) with different phenotypes (preserved ejection fraction (HFpEF), mildly reduced (HFmrEF) or reduced ejection fraction (HFrEF)), valvular heart disease (VHD), and atrial fibrillation (AF), specifically in women.
Keywords: cardiovascular disease, cardiovascular risk factors, Women, Heart Failure, Atrial Fibrillation, coronary heart disease, Valvular Heart Disease
Received: 16 Feb 2025; Accepted: 23 Jul 2025.
Copyright: © 2025 Charfeddine, Abid, Chenik, Ghrab, Haddar, Ben Krayen, Boudiche, Touati, Ayedi, Ammar, Ben Halima, Ben Ayed, Brahim, ElAyech, Thabet, Mahfoudhi, Jabloun, Ayadi, Ayadi, Romdhani, Gargouri, Zidi, Guedri, Tlili, Trabelsi, Hammami, Othmen, Antit, Saidane, Dardour, Iddir, Kharrat, Cheikhrouhou, Derwich, Mrabet, Lassoued, Rekik, Gmiha, Laribi, Lamine, Triki, Ayari, Boujelbene, Boughzela, Rekik, Ben Ameur, Abid, Oueghlani, Haggui, Ben Halima, Ouechtati, Bennour, Hammami, Jabeur, Zairi, Drissa, Addad, Milouchi, Mourali, Ben Slima, Bezdah, Neffati, Ben Ameur, Kraiem, Kachboura, Kammoun, Zakhama, lbn Hadj Amor, Ben Hamda, Messoudi, Ben Hlima, Dahmani, Gamra, Ibn Elhadj, Denguir, Ghorbel, Mechri, Ernez Hajri, Mebazaa, Ben Dhaou, Trigui, Fehri and Abdessalem. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Salma Charfeddine, Cardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia
Houssem Thabet, Cardiology Department, Sahloul University Hospital, Sousse, Tunisia
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