Comparing the efficacy of different types of exercise therapy in patients with essential hypertension: a systematic review and network meta-analysis

Longcheng Liu¹Wang JiaLe¹Xiaodi Ji¹Anqi Wang¹Shuo Yang²Xiaojian Chi¹Lingqian Hu¹Baolin Zhang¹Lihong Ma^1*

• ¹Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
• ²Xi'an Jiaotong University, xian, China

Objective: To compare the efficacy of different types of exercise modalities such as Tai Chi, Baduanjin, and Aerobic exercise in the treatment of hypertension. Methods: This article retrieved randomized controlled trials (RCTs) from the establishment of databases such as CNKI, WanFang, VIP, CBM, PubMed, Embase, Web of Science, and Cochrane Library to December 9, 2024. After assessing the risk of bias using the Cochrane risk of bias tool, a network meta-analysis was performed using Rev Man 5.4 and Stata 15 software. The primary outcome indicator of this article is Ambulatory Blood Pressure Measurement (ABPM), which includes 24-hour average systolic blood pressure (SBP) and 24-hour average diastolic blood pressure (DBP). Results: A total of 63 RCTs meeting the criteria were included, involving 5663 patients. The network meta-analysis results showed that compared with the control group, Light-intensity continuous training(LIAE)+antihypertensive medication [WMD = -1.82, 95%CI,(-2.93,-0.71)] was the most effective intervention for lowering SBP. For lowering DBP, Wuqinxi+ antihypertensive medication [WMD =-2.78 , 95% CI,(-4.1,-1.45)] was the most effective intervention. And the differences were statistically significant (P < 0.05). Conclusion: Exercise therapy combined with antihypertensive drugs may achieve a more significant blood pressure-lowering effect, and LICT, Wuqinxi, and Liuzijue may be higher priority options.