ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Cardiovascular Epidemiology and Prevention
Systematic Analysis and Comparison of the Burden of Cardiovascular Diseases in China from 1990 to 2021 and Its 15-Year Prediction with Global Levels
Provisionally accepted
- 1Affiliated Hospital of Guilin Medical University, Guilin, China
- 2The First Affiliated Hospital of Guangxi Medical University, Nanning, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Background and aims: Systematic assessment of cardiovascular disease (CVD) risk factors is crucial for prevention. We used GBD 2021 data to examine long-term trends and epidemiological features of CVDs in China and globally. Methods and results: CVD prevalence, incidence, mortality, and DALYs were analyzed using joinpoint regression, age-period-cohort models, decomposition, ARIMA, and BAPC. From 1990 to 2021, age-standardized mortality and DALY rates declined, but prevalence and case numbers increased, with males bearing a higher burden. Conclusion: Rapid population aging sustains high CVD burden, highlighting the urgent need for targeted prevention and management strategies.
Keywords: Cardiovascular Diseases, disease burden, China, global, gender disparities
Received: 14 Jul 2025; Accepted: 19 Nov 2025.
Copyright: © 2025 Gan, KE, Yang, Mo, Wang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jin-yi Li, 17834968@qq.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.