CASE REPORT article
Front. Cardiovasc. Med.
Sec. Thrombosis and Haemostasis
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1666077
This article is part of the Research TopicCase Reports in Thrombosis: 2025View all 10 articles
Concurrent Hemorrhage and Thrombosis: A Case Report of Hemoptysis from Pulmonary Vein Stenosis with Left Ventricular Thrombus
Provisionally accepted- Wuhan Sixth Hospital, Wuhan, China
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We report a rare case of concurrent pulmonary vein stenosis (PVS) and left ventricular thrombus (LVT) in a 46-year-old male with dilated cardiomyopathy and prior radiofrequency catheter ablation for atrial fibrillation, who presented with hemoptysis and dyspnea. Imaging confirmed left pulmonary vein occlusion and LVT, creating a therapeutic conflict between bleeding control and anticoagulation. We implemented a staged strategy: urgent balloon angioplasty and large-diameter bare-metal stent implantation to improve PVS hemodynamics and halt hemoptysis; subsequently, rivaroxaban and clopidogrel were initiated for LVT. At 6-month follow-up, symptoms resolved with complete LVT absorption, though LIPV developed in-stent re-occlusion. This demonstrated that prioritizing PVS intervention before anticoagulation effectively balances hemorrhage and thrombosis risks in this complex scenario.
Keywords: Pulmonary vein stenosis, Left ventricular thrombus, Radiofrequencycatheter ablation, Hemoptysis, In-stent Restenosis
Received: 15 Jul 2025; Accepted: 14 Aug 2025.
Copyright: © 2025 Chen, Yu, Liu, Liu, Qin, Zhu, Chen, Li and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Chenghong Li, Wuhan Sixth Hospital, Wuhan, China
Fajiu Li, Wuhan Sixth Hospital, Wuhan, China
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