CASE REPORT article
Front. Cardiovasc. Med.
Sec. Cardiovascular Surgery
Case Report: Right Pulmonary Artery Resection with Artificial Vascular Graft Replacement under Cardiopulmonary Bypass for Pulmonary Artery Angiomatoid Fibrous Histiocytoma
Tumin Sha 1,2
Jianqiang Li 3
Qian-li Wang 3
Chao Song 1,2
Xiaoxia Li 3
Chaoliang Liu 3
1. Binzhou Medical University, Binzhou, China
2. Binzhou Medical University - Yantai Campus, Yantai, China
3. Yantai Yuhuangding Hospital, Yantai, China
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Abstract
This report describes an extremely rare case of primary right pulmonary artery angiomatoid fibrous histiocytoma (AFH). A 51-year-old female was admitted with "chest tightness and dizziness for over two months, aggravated by chest pain for three days". Contrast-enhanced chest CT revealed an irregular filling defect (approximately 2.9×1.8 cm) in the right trunk of the pulmonary artery. The tumor in the right pulmonary artery was completely resected, followed by artificial vascular graft replacement under cardiopulmonary bypass with transection of the ascending aorta. Pathological examination confirmed AFH, with fluorescence in situ hybridization showing MDM2 (-, no amplification) and EWSR1 (+, break). No recurrence or metastasis of the tumor was observed during the five-month follow-up. Transection of the ascending aorta under cardiopulmonary bypass provided optimal exposure, enabling complete resection of the tumor while preserving right lung function through artificial vascular graft reconstruction, thereby achieving satisfactory clinical outcomes. This approach offers an effective surgical strategy for the management of pulmonary artery tumors, including AFH.
Summary
Keywords
Angiomatoid fibrous histiocytoma, Artificial vascular graft replacement, Cardiopulmonary Bypass, Pulmonary artery tumor, Transection of ascending aorta
Received
08 September 2025
Accepted
06 February 2026
Copyright
© 2026 Sha, Li, Wang, Song, Li and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Chaoliang Liu
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