CASE REPORT article
Front. Cardiovasc. Med.
Sec. Structural Interventional Cardiology
FluoroCT imaging -Guided Transapical Closure of MPL Preoperative FluoroCT imaging -Guided Transapical Closure of Mitral Paravalvular Leak: A Case Report
Qiong Luo
Ya Li
Hongkun Wu
Hao Chen
Chongqing General Hospital, Chongqing, China
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Abstract
Word count: 201 Background: Mitral paravalvular leak (PVL) is a recognized complication following prosthetic valve replacement, associated with heart failure, hemolysis, and increased morbidity. While redo surgery is the traditional treatment, transcatheter closure has emerged as a less invasive alternative, particularly in high-risk surgical candidates. Here, we present a case of preoperative FluoroCT imaging planning for transapical closure of mitral PVL. Case Presentation: A 57-year-old female with prior double mechanical valve replacement (mitral and aortic) presented with worsening exertional dyspnea and fatigue. Transesophageal Echocardiography (TEE) identified a 5 mm posterior paravalvular leak adjacent to the mitral sewing ring. Preoperative contrast-enhanced CT analyzed with FluoroCT imaging software localized the leak to the 4– 5 o'clock position and provided the optimal C-arm projection (cranial 48°, left anterior oblique 8°). Transapical closure via a left mini-thoracotomy was performed, and a 10 mm Ventricular Septal Defect occluder(Huayishengjie Medical Company, Beijing, China)was successfully deployed under TEE and fluoroscopic guidance. The patient had no residual leak, and total procedure time was 1 hour. Conclusions: FluroCT imaging-guided preoperative CT planning enables accurate localization of PVL and optimal fluoroscopic projection, reducing procedure time and improving safety. Transapical closure remains a feasible and effective approach for posterior mitral PVLs in complex double-valve patients.
Summary
Keywords
Closure of Mitral Paravalvular Leak, FluoroCT imaging -Guided, Minimally invasive, precise preoperative positioning, Transapical
Received
09 December 2025
Accepted
18 February 2026
Copyright
© 2026 Luo, Li, Wu and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Hongkun Wu
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