Frontiers in Cardiovascular Medicine | Cardiovascular Pharmacology and Drug Discovery

Systematic Review

Published on 26 May 2025

Methods and validity indicators for measuring adherence and persistence to aspirin in secondary cardiovascular prevention: a systematic review

in Cardiovascular Pharmacology and Drug Discovery

Rauf Nouni-García
Elisabeth Ramirez-Familia
Adriana López-Pineda
Amanda Esquerdo-Arroyo
Álvaro Carbonell-Soliva
María Martínez-Muñóz
Antonio F. Compañ Rosique
Jose A. Quesada
Concepción Carratalá-Munuera
Vicente F. Gil-Guillén

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1570331

595 views

Review

Published on 26 May 2025

Chinese medicine targets cellular autophagy against cardiovascular diseases: research progress and future prospects

in Cardiovascular Pharmacology and Drug Discovery

Zhengyu Chen
Jinjin Dou
Xiwu Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1585407

472 views

Original Research

Published on 23 May 2025

Yellow Wine Polyphenolic Compounds protect against myocardial ischemia-reperfusion injury in rats by activating Nrf2 nuclear translocation to regulate the balance of mitochondrial fission and fusion

in Cardiovascular Pharmacology and Drug Discovery

Lili Xu
Jiedong Zhou
Haifei Lou
Haodi Gu
Haixia Xu
Zuoquan Zhong
Hui Lin
Chengjian Jiang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1506388

569 views

Original Research

Published on 16 May 2025

Treatment adherence, persistence, and effectiveness of fixed dose combination versus free combination therapy of rosuvastatin–ezetimibe as a lipid-lowering therapy

in Cardiovascular Pharmacology and Drug Discovery

Mihail Samnaliev
Irfan Khan
Praveen Potukuchi
Kelly Lee
Genevieve Garon
Charlie Nicholls

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1461416

1,312 views

Original Research

Published on 12 May 2025

Genetic and clinical determinants of MACE and haemorrhage in antiplatelet therapy: insights from pharmacogenomic analysis

in Cardiovascular Pharmacology and Drug Discovery

Yubo Wang
Shuangli Yuan
Muyun Li
Wenling Feng
Jing Li
Wenwen Chen
Aliye Berdi
Yulian Kou
Yuan Yuan
Jun Zhao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1572389

803 views

Original Research

Published on 09 May 2025

Brown adipocyte-derived exosomes in type 2 diabetes mellitus impair endothelial function via regulating intracellular calcium cycle

in Cardiovascular Pharmacology and Drug Discovery

Xiaojie Ruan
Wei Zhao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1546325

923 views

Original Research

Published on 06 May 2025

Adverse events associated with amlodipine: a pharmacovigilance study using the FDA adverse event reporting system

in Cardiovascular Pharmacology and Drug Discovery

Xingwei Di
Jiazhen Jiang
Qian Zhong
Xinyu Zhou
Lisi Zhou
Jiyuan Zheng
Bingshuo Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1504671

1,485 views

Editorial

Accepted on 05 May 2025

Editorial: Therapeutic Strategies to Lower Residual Dyslipidemic CV Risk Beyond LDL-C and Statins

in Cardiovascular Pharmacology and Drug Discovery

Raffaele De Caterina
Matthew Budoff
William Boden

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1597062

114 views

Original Research

Published on 01 May 2025

Drug-induced cardiac arrest: a pharmacovigilance study from 2004–2024 based on FAERS database

in Cardiovascular Pharmacology and Drug Discovery

Gaocan Ren
Pingping Huang
Jinhui Zhang
Jin Liu
Zian Yan
Xiaochang Ma

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1498700

1,725 views

Original Research

Published on 28 Apr 2025

From knowledge silos to integrated insights: building a cardiovascular medication knowledge graph for enhanced medication knowledge retrieval, relationship discovery, and reasoning

in Cardiovascular Pharmacology and Drug Discovery

Hongzhen Cui
Xiaoyue Zhu
Wei Zhang
Meihua Piao
Yunfeng Peng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1526247

1,010 views

Original Research

Published on 22 Apr 2025

Integrating network pharmacology and experimental validation to investigate the mechanism of Gualou Xiebai Banxia decoction against myocardial ischemia

in Cardiovascular Pharmacology and Drug Discovery

Wanjun Zhu
Ping Shao
Ying Ren
Wenxuan Liu
Xiaorui Han
Kexin Zeng
Chunmei Dai
Feifei Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1512791

1,202 views

Original Research

Published on 22 Apr 2025

Mechanism of Ershen Zhenwu Decoction in ameliorating chronic heart failure via JNK/MAPK-regulated apoptosis: insights from network pharmacology and experimental validation

in Cardiovascular Pharmacology and Drug Discovery

Yulong Liu
Xinyue Wang
Maomao Zhang
Dan Cheng
Zhenpeng Zhu
Lan Ge
Xiaoyu Cheng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1561963

1,124 views

Brief Research Report

Published on 14 Mar 2025

Cross-Sectional analysis of demographic and clinical characteristics of patients in the United States using icosapent ethyl

in Cardiovascular Pharmacology and Drug Discovery

Peter P. Toth
John R. Nelson
Handrean Soran
Om P. Ganda
Nathan D. Wong
Hakima Hannachi
David Abrahamson
Josh Hartman
Sierra Luciano
Sephy Philip

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1411233

1,145 views

Original Research

Published on 20 Feb 2025

A comprehensive study on the impact of Ligustrum vicaryi L. fruit polysaccharide on myocardial fibrosis through animal experiments, network pharmacology and molecular docking

in Cardiovascular Pharmacology and Drug Discovery

Shuling Liu
Meifang Liu
Jianan Wang
Ruixue Rong
Yanwei Gao
Xiaoqi Li
Xin Liu
Shaojian Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1470761

1,635 views

Original Research

Published on 13 Feb 2025

Network pharmacology to unveil the blood components and mechanisms of Tongmai Yangxin Pills in treating elderly coronary heart disease

in Cardiovascular Pharmacology and Drug Discovery

Yue Zhang
Chao-Hui Li
Yi-Zhi Yan
Jie-Yun Lin
Shan-Shan Zhu
Si-Jie Tan
Peng Zeng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1475546

2,277 views
1 citation

Systematic Review

Published on 15 Jan 2025

Efficacy and safety of cardiac myosin inhibitors for symptomatic hypertrophic cardiomyopathy: a meta-analysis of randomized controlled trials

in Cardiovascular Pharmacology and Drug Discovery

Anas Abunada
Madiha Shah
Ateesh Kumar
Syeda Lamiya Mir
Dinesh Kumar
Saboor Ahmed
Muhammad Tanzeel
Vikash Kumar
Aashish Meghjiani
Muhammad Basit Ali Siddiqui

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1477487

2,500 views