Frontiers in Cardiovascular Medicine

Review

Published on 13 Aug 2026

Machine learning and multi-omics technologies for precision cardiovascular medicine: advancing diagnosis, risk prediction, and therapeutic guidance

in Precision Cardiology

Yaqi Dai
Liufang Wu
Hanliangqi Xue
Liru Zhou
Yahan Yang
Xinyu Wang
Yanru Lai
Yating Tang
Haoxiang Huang
Sifei Chen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1921962

338 views

Original Research

Accepted on 12 Aug 2026

Cardiac and Systemic Biological Age Capture Complementary Aging Signals Associated with Cardiovascular Disease

in Precision Cardiology

Yiming Wang
Hao Zhu
Xiaotong Liu
Chenwen Yuan
Jing Liu
Yu Duan

Frontiers in Cardiovascular Medicine

Original Research

Accepted on 30 Jul 2026

Quantum-Optimized Spatio-Temporal Transformer for Multimodal Cardiovascular Risk Prediction from Clinical and Wearable Data

in Precision Cardiology

Sathya S
Saranya K

Frontiers in Cardiovascular Medicine

131 views

Original Research

Accepted on 28 Jul 2026

Machine Learning-Based Early Identification of Heart Failure/Congestion Complicating Acute Coronary Syndrome Using Body Composition Analysis: A Retrospective Cohort Study

in Precision Cardiology

Yanting Sun
Zhaobin He
Yongzhe Yu

Frontiers in Cardiovascular Medicine

153 views

Perspective

Published on 28 Jul 2026

Redefining cardiometabolic biomarkers in the big data era: toward a personalized medicine-centered reconstruction of risk prediction models

in Precision Cardiology

Xin-zhe Jiang
Li-jiao Guo
Ming-tian Zhang
Guang-ling Ji
Hong-tao Liu
Yue Zheng
Jie Zhou

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1846105

405 views

Clinical Trial

Published on 21 Jul 2026

Assessing the diagnostic accuracy of cardisiography in the diagnosis of coronary heart disease: CSG-DR study (A pilot study)

in Precision Cardiology

Rafael A. Guillén-Marmolejos
Rodolfo A. Núñez-Musa
Alberto J. Núñez-Selles
Ana J. Santos-Rondón
Miguel Arias-Ceballos
the CSG Group

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1845141

764 views

Policy Brief

Published on 13 Jul 2026

Precision cardiovascular medicine: global imperative for equity through innovation

in Precision Cardiology

Jose R. Medina-Inojosa
Fatima Rodriguez
Francisco Lopez-Jimenez
Laurence S. Sperling

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1835607

941 views

Review

Published on 13 Jul 2026

The detection of cardiovascular biomarkers in dermal interstitial fluid - a step to real-time monitoring

in Precision Cardiology

Yousaf Bhatti
Alireza Yazdi
Daniel A. Jones
Didier Locca
Pankaj Vadgama
Adrian Mihai Ionescu
Anthony Mathur

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1724051

1,210 views

Review

Published on 06 Jul 2026

Dynamic navigation-based precision cardiac rehabilitation via blood metabolomics: from risk stratification to real-time intervention optimization

in Precision Cardiology

Hejuan Hua
Yanbing Chen
Tianyi Yu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1805494

899 views

Original Research

Published on 29 Jun 2026

Systematic benchmark of reduced-lead configurations for 12-lead ECG reconstruction: multi-model evaluation across all possible subsets

in Precision Cardiology

Xinyu Zhang
Hailing Cai
Huilong Duan
Xudong Lu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1856211

1,119 views

Original Research

Published on 25 Jun 2026

Succinylation-annotated genes in AMI: multi-omics and single-cell prioritization of ASGR2 and NPL

in Precision Cardiology

Jie Yu
Xu Ma
Jing Fang
Yingying Liu
Cong Wang
Shuxia Shi
Kaile Wang
Yunlun Li
Lei Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1836786

860 views

Original Research

Published on 24 Jun 2026

Association of ABCB1 and CYP2C19 polymorphisms with major adverse cardiovascular complications in patients taking clopidogrel

in Precision Cardiology

Lubna Q. Khasawneh
Mais N. Alqasrawi
Zeina N. Al-Mahayri
Lilas Dabaghie
Sahar M. Altoum
Gohar Jamil
Salahdein Aburuz
Dana Hamza
Lizy George
Faiz Al-Bakshy

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1844931

1,127 views

Original Research

Published on 11 Jun 2026

Utility of miRNA biomarkers in patients with acute myocardial infarction (UNIAMI)—results from a prospective pilot study

in Precision Cardiology

Chakradhara Rao S. Uppugunduri
Koustav Sarkar
Oishi Mukherjee
Kaviya Manoharan
Iyshwarya B. K
Melvin George

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1730999

1,580 views

Systematic Review

Published on 08 Jun 2026

Federated learning for cardiovascular disease prediction: a systematic review of clinical applications, validation, and translation readiness

in Precision Cardiology

Jie Li
Wei Xiang
Dandan Shang
Shujuan Li
Qin Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1831342

2,077 views

Review

Published on 25 May 2026

Research advances in chronic thromboembolic pulmonary hypertension: from pathological mechanisms to multidisciplinary management

in Precision Cardiology

Juan-Juan Zhang
Yu-Qian Huang
Xue-Kai Liu
Xiao-Long Sun
Xiang Zhong
Chuan Zhou
Chao Wang
Ping Xie

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1832792

1,989 views

Original Research

Published on 11 May 2026

Myocardial fibrosis and tissue alterations predict cardiovascular outcomes in chronic kidney disease—a prospective virtual twin study design using large-scale population database

in Precision Cardiology

Georgios Vavilis
Yeshe M. Kway
Zahra Raisi-Estabragh
Steffen E. Petersen
Stefan Neubauer
Qiang Zhang
Vanessa M. Ferreira
Stefan K. Piechnik

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1726445

1,482 views

Original Research

Published on 29 Apr 2026

Atrial fibrillation type-specific prediction of recurrence after catheter ablation: the pivotal role of right atrial remodeling revealed by explainable machine learning

in Precision Cardiology

Xiaonan Han
Tianyun Liu
Meng Li
Yirong Liu
Fang Li
Tong Pan
Dongyan Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1805262

1,592 views

Original Research

Published on 02 Apr 2026

Evaluation of large language models in percutaneous coronary intervention decision-making

in Precision Cardiology

Chengze Lin
Yongying Lan
Zi Zeng
Lingfang Zhuang
Rui Dai
Gang Lv
Yun Xie
Qi Jin
Liqun Wu
Qing Cao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1690716

1,921 views

Original Research

Published on 19 Mar 2026

Predictors of patient-perceived functional improvement after cardiac resynchronization therapy: a real-world multi-dimensional analysis of clinical, imaging, and ECG predictors

in Precision Cardiology

Ahmad Samir
Amr Yosry Emam
Rehab Elnagar
Shaimaa Nabil
Mahmoud Abdelfattah
Nevine Abdelmegeed
Eslam Ahmed
Omnia Kamel
Karimeldeen Hafez

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1742350

2,195 views

Perspective

Published on 13 Mar 2026

From acute diagnosis to longitudinal risk stratification: a paradigm shift in the clinical role of cardiac biomarkers

in Precision Cardiology

Hong Zheng
Xue Li
Li-Jiao Guo
Guang-Ling Ji
Hong-Tao Liu
Yue Zheng
Jie Zhou

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1778456

2,815 views

Case Report

Published on 12 Mar 2026

Chronic Brucella infection associated with amyloid light chain cardiac amyloidosis: a case report

in Precision Cardiology

RuiXia He
HaiJun Wang
LingMin Wu
Li Li
XinYuan Xu
GuoLi Ma
BaYaEr Qi
LiNa Ji
XiaoPing Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1703993

1,922 views

Review

Published on 19 Feb 2026

Precision medicine and personalized nursing in cardiovascular disease: clinical applications and frontier developments

in Precision Cardiology

Xiaolan He
Guiying You

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1616059

3,718 views
2 citations

Original Research

Published on 16 Feb 2026

Precision patient selection for ablate-and-pace: a multi-center study comparing leadless pacemaker vs. standard pacemaker in patients with indication to ablate-and-pace for atrial fibrillation (LEAD-AP)

in Precision Cardiology

Ingrid Overeinder
Luigi Pannone
Domenico Laviola
Wael Zaher
Giacomo Mugnai
Gianmarco Arabia
Ivan Eltsov
Ioannis Doundoulakis
Domenico Giovanni Della Rocca
Paul-Adrian Calburean

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1741074

1,619 views

Review

Published on 09 Feb 2026

From polygenic risk to digital twins: the future of personalised cardiovascular medicine

in Precision Cardiology

Ibrahim Antoun
Alkassem Alkhayer
Ahmed Abdelrazik
Mahmoud Eldesouky
Kaung Myat Thu
Mokhtar Ibrahim
Harshil Dhutia
Riyaz Somani
G. Andre Ng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1735094

3,341 views
2 citations

38 articles

articles

Machine learning and multi-omics technologies for precision cardiovascular medicine: advancing diagnosis, risk prediction, and therapeutic guidance

Cardiac and Systemic Biological Age Capture Complementary Aging Signals Associated with Cardiovascular Disease

Quantum-Optimized Spatio-Temporal Transformer for Multimodal Cardiovascular Risk Prediction from Clinical and Wearable Data

Machine Learning-Based Early Identification of Heart Failure/Congestion Complicating Acute Coronary Syndrome Using Body Composition Analysis: A Retrospective Cohort Study

Redefining cardiometabolic biomarkers in the big data era: toward a personalized medicine-centered reconstruction of risk prediction models

Assessing the diagnostic accuracy of cardisiography in the diagnosis of coronary heart disease: CSG-DR study (A pilot study)

Precision cardiovascular medicine: global imperative for equity through innovation

The detection of cardiovascular biomarkers in dermal interstitial fluid - a step to real-time monitoring

Dynamic navigation-based precision cardiac rehabilitation via blood metabolomics: from risk stratification to real-time intervention optimization

Systematic benchmark of reduced-lead configurations for 12-lead ECG reconstruction: multi-model evaluation across all possible subsets

Succinylation-annotated genes in AMI: multi-omics and single-cell prioritization of ASGR2 and NPL

Association of ABCB1 and CYP2C19 polymorphisms with major adverse cardiovascular complications in patients taking clopidogrel

Utility of miRNA biomarkers in patients with acute myocardial infarction (UNIAMI)—results from a prospective pilot study

Federated learning for cardiovascular disease prediction: a systematic review of clinical applications, validation, and translation readiness

Research advances in chronic thromboembolic pulmonary hypertension: from pathological mechanisms to multidisciplinary management

Myocardial fibrosis and tissue alterations predict cardiovascular outcomes in chronic kidney disease—a prospective virtual twin study design using large-scale population database

Atrial fibrillation type-specific prediction of recurrence after catheter ablation: the pivotal role of right atrial remodeling revealed by explainable machine learning

Evaluation of large language models in percutaneous coronary intervention decision-making

Predictors of patient-perceived functional improvement after cardiac resynchronization therapy: a real-world multi-dimensional analysis of clinical, imaging, and ECG predictors

From acute diagnosis to longitudinal risk stratification: a paradigm shift in the clinical role of cardiac biomarkers

Chronic Brucella infection associated with amyloid light chain cardiac amyloidosis: a case report

Precision medicine and personalized nursing in cardiovascular disease: clinical applications and frontier developments

Precision patient selection for ablate-and-pace: a multi-center study comparing leadless pacemaker vs. standard pacemaker in patients with indication to ablate-and-pace for atrial fibrillation (LEAD-AP)

From polygenic risk to digital twins: the future of personalised cardiovascular medicine