CORRECTION article

Front. Cell Dev. Biol., 23 June 2021

Sec. Molecular and Cellular Pathology

Volume 9 - 2021 | https://doi.org/10.3389/fcell.2021.671532

Corrigendum: Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties

  • 1. Institute of Biochemistry, Christian-Albrechts-Universität zu Kiel, Kiel, Germany

  • 2. Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

  • 3. Institute of Anatomy, Christian-Albrechts-Universität zu Kiel, Kiel, Germany

  • 4. Institute of Anatomy, Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany

In the original article, there was a mistake in Figure 1C as published. In the Coomassie brilliant blue (CBB) protein staining, which was used as additional loading control (besides GAPDH), 11 instead of 10 sample lanes (+ protein ladder) were shown in the original Figure 1C. This mistake resulted from an additional sample (transfection control), that was loaded on the far right. This lane was not shown in both immunoblots (CTSD and GAPDH), but accidentally was still shown in the CBB control. The corrected Figure 1C appears below.

Figure 1

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

References

  • 1

    GradlerU.CzodrowskiP.TsaklakidisC.KleinM.WerkmannD.LindemannS.et al. (2014). Structure-based optimization of non-peptidic Cathepsin D inhibitors. Bioorg. Med. Chem. Lett.24, 41414150. 10.1016/j.bmcl.2014.07.054

Summary

Keywords

lysosomal degradation, molecular dynamics simulation, Parkinson's disease, neuronal ceroid lipofuscinoses, lysosomes, alpha-synuclein, cathepsin D

Citation

Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P and Zunke F (2021) Corrigendum: Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties. Front. Cell Dev. Biol. 9:671532. doi: 10.3389/fcell.2021.671532

Received

24 February 2021

Accepted

07 June 2021

Published

23 June 2021

Volume

9 - 2021

Edited by

Masaru Katoh, National Cancer Centre, Japan

Reviewed by

Claudia Fiorillo, University of Florence, Italy

Updates

Copyright

*Correspondence: Friederike Zunke

This article was submitted to Molecular Medicine, a section of the journal Frontiers in Cell and Developmental Biology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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