CORRECTION article

Front. Cell Dev. Biol., 20 May 2021

Sec. Stem Cell Research

Volume 9 - 2021 | https://doi.org/10.3389/fcell.2021.684641

Corrigendum: Dissecting the Niche for Alveolar Type II Cells With Alveolar Organoids

  • 1. Department of Haematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

  • 2. Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

In the original article, there was a mistake in Supplementary Table 1 as published. In the original article, the correspondence author inappropriately included a table of an unpublished manuscript. The corrected Supplementary Table 1 appears below.

Supplementary Table 1

Supporting cellsCulture methodGFs/inhibitors included in basic mediumReferences
Primary lung FibroblastsAEC2 cells were cultured on top of a single layer of fibroblasts in Matrigel matrixSucre et al., 2018
Primary fibroblasts or fibroblast cell lineAEC2 cells were mixed with supporting cells in Matrigel/culture medium, seeded into transwell insert for coculture. Culture medium supplemented with growth factors and inhibitors was changed regularly for organoid growth.Y-27632, ITS, SB431542Chen et al., 2012;
Barkauskas et al., 2013;
Zacharias et al., 2018
Lung mesenchymal cellsITSMcQualter et al., 2010
lung endothelial cellsITSLee et al., 2014
CD45+;F4/80+ MacrophagesITS, EGF, KGF, FGF2, HGFLechner et al., 2017
Supporting cell-freeAEC2 cells were embedded in Matrigel matrix for culture. Growth factors and inhibitors were added into the culture medium to stimulate the growth of AEC2 cells.Jagged-1,Noggin, SB431542,CHIR-99021, KGF, Y-27632Shiraishi et al., 2019a,b
A83-1, Noggin, Rspo1, Wnt3a, EGF, KGF, FGF10, Y-27632Weiner et al., 2019

Organotypic culture methods of AEC2 cells.

ITS, insulin, transferrin and selenium; KGF, keratinocyte growth factor; EGF, epidermal growth factor; FGF2, fibroblast growth factor 2; FGF10, fibroblast growth factor 10; HGF, Hepatocyte growth factor; Rspo1, R-spondin 1.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Summary

Keywords

lung, alveolar epithelium, alveolar type II epithelial cell, alveolar stem cell, alveolar organoid, Wnt pathway, FGF pathway, coronavirus

Citation

Liao D and Li H (2021) Corrigendum: Dissecting the Niche for Alveolar Type II Cells With Alveolar Organoids. Front. Cell Dev. Biol. 9:684641. doi: 10.3389/fcell.2021.684641

Received

23 March 2021

Accepted

30 March 2021

Published

20 May 2021

Volume

9 - 2021

Edited and reviewed by

Eumorphia Remboutsika, National and Kapodistrian University of Athens, Greece

Updates

Copyright

*Correspondence: Huaibiao Li

This article was submitted to Stem Cell Research, a section of the journal Frontiers in Cell and Developmental Biology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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