In the published article, there was an error in the legend of Figure 2 as published. The expression level of glial Draper with loss of neuronal FMRP was mistakenly summarized. Based on the conclusion of our reviewed paper, loss of neuronal FMRP should decrease the expression level of glial Draper. The corrected Figure 2 legend appears below:
Figure 2 | Secreted signals regulated by neuronal FMRP orchestrate glial phagocytosis. In early adult Drosophila brain PDF-Tri neurons, FMRP is proposed to promote the secretion of insulin-like peptides (ILPs) that drive glial insulin receptor phosphorylation (InR-P) to trigger glial phagocytosis of neuronal processes. In the glia, Draper (Drpr) phagocytosis receptor expression is decreased by loss of neuronal FMRP. However, the neuronal Drpr ligands (for example, Pretaporter, phosphatidylserine) involved in this FMRP-dependent mechanism remain unknown. Neuronal FMRP may regulate numerous other “find me” and “eat me” secreted neural signals that recruit glia and instruct glial phagocytosis, ranging from individual synapses to whole brain neurons.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Statements
Publisher’s note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Summary
Keywords
bone morphogenetic protein, insulin-like peptide, fragile x mental retardation protein, wingless, Drosophila
Citation
Song C and Broadie K (2024) Corrigendum: Dysregulation of BMP, Wnt, and insulin signaling in fragile X syndrome. Front. Cell Dev. Biol. 12:1416720. doi: 10.3389/fcell.2024.1416720
Received
13 April 2024
Accepted
14 May 2024
Published
04 June 2024
Volume
12 - 2024
Edited and reviewed by
Brian Storrie, University of Arkansas for Medical Sciences, United States
Updates
Copyright
© 2024 Song and Broadie.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Kendal Broadie, kendal.broadie@vanderbilt.edu
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.