EDITORIAL article
Front. Cell Dev. Biol.
Sec. Cell Growth and Division
Volume 13 - 2025 | doi: 10.3389/fcell.2025.1633691
This article is part of the Research TopicRehabilitation and Regeneration in Orthopaedic: From Cellular Regulation to Innovative Medical TechnologiesView all 5 articles
Editorial: Rehabilitation and Regeneration in Orthopaedic: From Cellular Regulation to Innovative Medical Technologies
Provisionally accepted
- 1Affiliated Zhongshan Hospital of Dalian University, Dalian, China
- 2The Hong Kong Polytechnic University, Hong Kong, Hong Kong, SAR China
- 3University of Texas, Dallas, United States
- 4University of California, Los Angeles, United States
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Orthopaedic rehabilitation and regeneration represent a transformative frontier in musculoskeletal medicine, where cutting-edge biological insights converge with advanced engineering innovations to reshape clinical development. This research topic compiles articles investigating the latest developments in cellular regulation, non-coding RNA biology, stem cell co-culture systems, and innovative medical technologies for orthopaedic applications.Additionally, these studies enhance the understanding of orthopaedic regeneration and provide practical strategies for clinical implementation. This collection underscores the necessity of hybrid solutions combining biological precision with engineered reliability, which aligns with the work of vascularized bone regeneration strategies, biofunctionalized bone grafts and additive manufacturing techniques by Zhao et al. [1][2] . Furthermore, these articles contribute to a deeper understanding of the cellular and molecular mechanisms governing bone healing and regeneration, showing potential translation of these innovative technologies in orthopaedic clinical practice. From the regulatory roles of non-coding RNAs to the development of advanced biomaterials and cell therapy strategies, the research presented in this topic highlights the interdisciplinary nature of current orthopaedic science. As the complexities of biology mechanisms and materials science are continually revealed, we are edging closer to realize more effective and personalized approaches to rehabilitation and regeneration in orthopaedic application.
Keywords: orthopeadic, Rehabilitation, Regeneration, cellular regulation, Biomaterials
Received: 23 May 2025; Accepted: 23 May 2025.
Copyright: © 2025 Wang, LI, Li, Yuan and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Dewei Zhao, Affiliated Zhongshan Hospital of Dalian University, Dalian, China
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