REVIEW article
Front. Cell Dev. Biol.
Sec. Cellular Biochemistry
Volume 13 - 2025 | doi: 10.3389/fcell.2025.1709461
This article is part of the Research TopicCell Authentication: Addressing Challenges and FindingsView all articles
Extracellular Vesicles in Laboratory Medicine: A Review and Outlook
Provisionally accepted
- 1Aerospace Center Hospital, Beijing, China
- 2People's Hospital of Ganzhou Economic Development Zone, Ganzhou, China
- 3Guizhou Aerospace Hospital, Zunyi, China
- 4First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Abstract Extracellular vesicles (EVs), serving as promising novel biomarkers for diseases, demonstrate extensive potential applications in disease diagnosis, prognosis evaluation, and treatment monitoring. Currently, EVs have made substantial advancements in the areas of disease diagnosis, prognosis, and treatment. Nevertheless, for EVs to be fully integrated into clinical laboratories, ongoing efforts are required in multi-omics integration and big data analysis, the development of clinically applicable separation and detection technologies, the establishment of standardized quality systems, as well as clinical trials and regulatory approval processes. This paper reviews the current status of the application of extracellular vesicles in disease diagnosis, prognostic assessment, and treatment monitoring, analyzes the challenges facing current research, and discusses future trends.
Keywords: extracellular vesicles, laboratory medicine, Disease diagnosis, Prognostic evaluation, Development trends
Received: 20 Sep 2025; Accepted: 16 Oct 2025.
Copyright: © 2025 Wang, Liu, Zhao, Shen, Jin, Rao and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Defa Huang, aa3716340@163.com
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