Frontiers in Cell and Developmental Biology

Original Research

Published on 06 Feb 2026

A transitional desmosome/tonofibril network may relay mechanical strain to epidermal nerve terminals with high fidelity and sensitivity in the Cuban crocodile (Crocodylus rhombifer): an ultrastructural study

Karl-Gunnar Melkersson
Monika Hodik
Karin Staxäng
Pierre Hakizimana
Hao Li
Helge Rask-Andersen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1739378

691 views

Brief Research Report

Accepted on 05 Feb 2026

Tumor Microenvironment-Activated Ferritin Nanovector Enables Enhanced Tumor Delivery of KRASG12C Inhibitors and Degraders

Annalisa Pia Abbinantefina
Claudia Tito
Silvia Masciarelli
Giada Tisci
Siria Sortoluzzi
Pierpaolo Ceci
ELISABETTA FALVO
Antonello Mai
Dante Rotili
Francesco Fazi

Frontiers in Cell and Developmental Biology

175 views

Review

Accepted on 05 Feb 2026

The Role of the Reproductive Tract and Follicular Fluid Microbiota in IVF/ICSI Pregnancy Outcomes: A Systematic Review of Microbial Diversity and Probiotic Interventions

Guangyu Ma
Leixi Peng
Rui Cai
Bixi He
Jinbiao Han
Rui Gao
Lang Qin

Frontiers in Cell and Developmental Biology

149 views

Original Research

Accepted on 05 Feb 2026

A novel kinase inhibitor, Regorafenib, blocks EGFR-dependent signaling to repress tumour metastasis in human triple-negative breast cancers

Ying Liu
Ludong Zhao
Chunxin Wang
Yanzhi Wang
Meijing Liu
Hongyu Du
Xiaohui Chu
Wenqiang Yang
Guan Wang
Bo Zhang

Frontiers in Cell and Developmental Biology

211 views

Original Research

Published on 05 Feb 2026

Stem cell therapy targets THBS1 to reverse endometrial fibrosis

Xiaochuan Yu
Lijuan Shi
MingBo Qu
Yonggang Zhang
Yating Zhang
Xinyu Xu
Lina Liu
Huanan Wang
Huali Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1766915

510 views

Original Research

Published on 05 Feb 2026

Multi-scale systems toxicology defines a KLF5-centered adverse outcome pathway linking DEHP exposure to pancreatic cancer progression and signaling programs relevant to therapy tolerance

Jihao Chen
Huaxin Pang
Jundan Wang
Junhua Guo
Ting Huang
Heran Zhou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1769023

664 views

Editorial

Published on 05 Feb 2026

Editorial: Advancing bone and soft tissue repair: bioengineering from cellular insights to clinical applications

Ya-xing Li
Long-mei Zhao
Hui Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1787852

449 views

Editorial

Published on 05 Feb 2026

Editorial: Early embryonic development lineage

Lu Zhang
Shoulong Deng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1785662

382 views

Review

Published on 05 Feb 2026

WWC proteins as emerging biomarkers and therapeutic targets in cancer pathogenesis

Shuge Wang
Junzhe Li
Xianhua Xu
Shijie Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1712319

450 views

Original Research

Published on 05 Feb 2026

Development of gold nanoparticles stabilized by PLGA and PVA for application in photothermal therapy

Soraia Borges
Natanael Fernandes
André F. Moreira

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1759401

605 views

Original Research

Published on 05 Feb 2026

Differential responses to the combination of navitoclax and venetoclax with doxorubicin in murine models of triple negative breast cancer

Homood M. As Sobeai
Abdulrahman M. Alanazi
Faisal Alotaibi
Ali Alhoshani
Khalid Alhazzani
Mashal M. Almutairi
Sultan Almudimeegh
Basel K. Al-Ramadi
Eesha Chakraborty
Tareq Saleh

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1661424

712 views

Original Research

Published on 05 Feb 2026

TRIM26 deficiency drives gastric cancer lymph node metastasis via TGF-β signaling activation and modulates gemcitabine response

Kanger Shen
Daojiang Liu
Jing Su
Sirui Shen
Haiyan Zhang
Wei Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1746425

522 views

Original Research

Accepted on 04 Feb 2026

Tumour suppressors LKB1 and SMARCA4 functionally interact to regulate gene expression of diverse biological processes in lung cancer

Mohammed Bourouh
Jinhong Kim
Paola A Marignani

Frontiers in Cell and Developmental Biology

139 views

Review

Accepted on 04 Feb 2026

Exerkine-Loaded Exosomes in Muscle Aging: A Nexus of Exercise, Regeneration, and Crosstalk

Yang Li
Qingzhong Wu
Junmin Wang
Jiahao Ding
Jinpeng He

Frontiers in Cell and Developmental Biology

160 views

Original Research

Accepted on 04 Feb 2026

DNA2 acts as a brake on β cell insulin hypersecretion and diet-induced metabolic dysfunction

Haixia Xu
Dongmei Tang
Na Yang
Meilin Ma
Yan Tian
Xianghui Fu

Frontiers in Cell and Developmental Biology

116 views

Original Research

Published on 04 Feb 2026

Global clinical trial landscape of stem cell-based therapies for osteoarthritis: trends and translational implications

Xin Li
Yue Zhao
Dongsheng Guo
Chen Yan
Jian Zhang
Lin Cheng
Yuefu Dong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1757935

795 views

Review

Published on 04 Feb 2026

Branched-chain amino acid transaminases as promising targets in tumor therapy

Weiran Zhang
Jie Shen
Xuanyin Ding
Hele Liu
Xu Wang
Dan Feng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1712076

436 views

Review

Published on 04 Feb 2026

The dual role of autophagy in cartilage degradation: from mechanisms to targeted therapeutics

Jiahua Mei
Shenghao Zhang
Xinrong Cui
Ruiping Yang
Jin Ke
Lili Cui
Lin Tan
Shan Zhu
Yunshu Ma

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1737547

472 views

Original Research

Published on 04 Feb 2026

A prospective pilot study on DACHAO intervention for improving embryo quality metrics in IVF/ICSI failure cases

Rui Xing
Lei Jiang
Jie Zhang
Xiao-Qi Zuo
Xin Xu
Meng-Chi Xue
Yi-Ran Zhao
Gui-Min Hao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1746912

483 views

Editorial

Published on 04 Feb 2026

Editorial: Application of novel biomarkers and natural compounds in precision oncology

Yuqing Li
Meng Zhang
Zhao Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1783190

403 views

Review

Accepted on 03 Feb 2026

Redox Regulation in Aging Muscles: Exercise as a Key Modulator to Combat Sarcopenia and Frailty

Wang Zhiming
Yang Gui
Zhanguo Su

Frontiers in Cell and Developmental Biology

126 views

Original Research

Accepted on 03 Feb 2026

LPS–TLR4 Signaling Attenuates CHOP-Mediated Apoptosis under Endoplasmic Reticulum Stress Conditions during Porcine Embryonic Development

Gyu-Hyun Lee
Cheng-Lin Zhan
Song-Hee Lee
Qin-Yue Lu
Ying-Yan Jin
Ji-Yeon Lee
Kyung-Tae Shin
Xiang-Shun Cui

Frontiers in Cell and Developmental Biology

161 views

Review

Accepted on 03 Feb 2026

Angiogenesis in ossification of the posterior longitudinal ligament: progress from mechanism to targeted intervention

Xiaoyu Liu
Xiaomin Wang
Kangyi Hu
Haonan Wen
Lu Liu
Haoxing Li
Zhixin Che
Ting Song
Jinquan Lai
Min Song

Frontiers in Cell and Developmental Biology

Brief Research Report

Accepted on 03 Feb 2026

Cell type-dependent suppression of the RNA helicase DDX3Y levels by the close paralog DDX3X

Xiaolu Xu
Nicholas F Grigoropoulos
Shuo Wei

Frontiers in Cell and Developmental Biology

192 views

13,020 Publications

volumes

Volume 14 - 2026

A transitional desmosome/tonofibril network may relay mechanical strain to epidermal nerve terminals with high fidelity and sensitivity in the Cuban crocodile (Crocodylus rhombifer): an ultrastructural study

Tumor Microenvironment-Activated Ferritin Nanovector Enables Enhanced Tumor Delivery of KRASG12C Inhibitors and Degraders

The Role of the Reproductive Tract and Follicular Fluid Microbiota in IVF/ICSI Pregnancy Outcomes: A Systematic Review of Microbial Diversity and Probiotic Interventions

A novel kinase inhibitor, Regorafenib, blocks EGFR-dependent signaling to repress tumour metastasis in human triple-negative breast cancers

Stem cell therapy targets THBS1 to reverse endometrial fibrosis

Multi-scale systems toxicology defines a KLF5-centered adverse outcome pathway linking DEHP exposure to pancreatic cancer progression and signaling programs relevant to therapy tolerance

Editorial: Advancing bone and soft tissue repair: bioengineering from cellular insights to clinical applications

Editorial: Early embryonic development lineage

WWC proteins as emerging biomarkers and therapeutic targets in cancer pathogenesis

Development of gold nanoparticles stabilized by PLGA and PVA for application in photothermal therapy

Differential responses to the combination of navitoclax and venetoclax with doxorubicin in murine models of triple negative breast cancer

TRIM26 deficiency drives gastric cancer lymph node metastasis via TGF-β signaling activation and modulates gemcitabine response

Tumour suppressors LKB1 and SMARCA4 functionally interact to regulate gene expression of diverse biological processes in lung cancer

Exerkine-Loaded Exosomes in Muscle Aging: A Nexus of Exercise, Regeneration, and Crosstalk

DNA2 acts as a brake on β cell insulin hypersecretion and diet-induced metabolic dysfunction

Global clinical trial landscape of stem cell-based therapies for osteoarthritis: trends and translational implications

Branched-chain amino acid transaminases as promising targets in tumor therapy

The dual role of autophagy in cartilage degradation: from mechanisms to targeted therapeutics

A prospective pilot study on DACHAO intervention for improving embryo quality metrics in IVF/ICSI failure cases

Editorial: Application of novel biomarkers and natural compounds in precision oncology

Redox Regulation in Aging Muscles: Exercise as a Key Modulator to Combat Sarcopenia and Frailty

LPS–TLR4 Signaling Attenuates CHOP-Mediated Apoptosis under Endoplasmic Reticulum Stress Conditions during Porcine Embryonic Development

Angiogenesis in ossification of the posterior longitudinal ligament: progress from mechanism to targeted intervention

Cell type-dependent suppression of the RNA helicase DDX3Y levels by the close paralog DDX3X