Frontiers in Drug Safety and Regulation

Original Research

Published on 04 Sep 2026

Global patterns and trends in spontaneous reporting systems: VigiBase, FAERS, VAERS, and JADER

in Clinical Drug Safety

Nikola Panajotovikj
Jordi Mestres

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2026.1919822

637 views

Original Research

Published on 25 Aug 2026

Psychotropic dispensing in Greek adolescents and young adults: national trends and regional variation

in Clinical Drug Safety

Konstantinos Kassandros
Maria Samakouri
Maria Panagopoulou
Theodoros Constantinidis
Christos Kontogiorgis

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2026.1900494

727 views

Perspective

Published on 12 Aug 2026

Deprescribing and Anti-CGRP preventive therapy in medication-overuse headache associated with migraine: pathophysiological rationale and single-center real world evidence

in Clinical Drug Safety

Matija Sošić
Valentino Rački
Almir Fajkić
Mladen Jašić
Andrej Belančić

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2026.1836444

796 views

Systematic Review

Published on 10 Jul 2026

Safety profile of small interfering RNA therapeutics: a systematic review and meta-analysis of randomized controlled trials

in Clinical Drug Safety

Cheewon Ahn
Hyunsuk Jeong
Hyeon Woo Yim
Na Jin Kim
Sungpil Han
Ilhoan Oh

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2026.1855572

1,577 views

Review

Published on 11 Jun 2026

The cutaneous mirror: leveraging drug-induced skin phenotypes as early visual risk signals for systemic toxicity, a comprehensive review

in Clinical Drug Safety

Hind B. Alshalhoob
Lama M. Albelowi
Aseel S. Alotaibi
Shada Khalid Alanazi
Leen E. Alturki
Zahra Saleh Alsindi
Waad Abdulelah Alduraywish
Sarah Anwar Almulla
Ahmed Anwar Almulla
Nouf Abdulaziz Almagushi

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2026.1825005

2,424 views

Original Research

Published on 10 Jun 2026

Comprehensive pharmacovigilance assessment of pairwise drug–drug interactions and acute pancreatitis in the FDA adverse event reporting system: focus on incretin-based drugs

in Clinical Drug Safety

Issei Kazume
Kenji Onda
Sachiko Tanaka
Takashi Yokokawa
Kenichi Suzuki

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2026.1827098

1,880 views

Brief Research Report

Published on 08 Jun 2026

Modafinil and abnormal bleeding in a young lady with narcolepsy: a case report

in Clinical Drug Safety

Albatol N. Rashed
Ahmed Abdelbasit
Mana Alshahrani

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2026.1767644

1,997 views

Original Research

Published on 08 May 2026

Colistin use and outcomes in Kuwait public hospitals

in Clinical Drug Safety

Sarah S. Alghanem
Wadha A. Alfouzan
Moetaza M. Soliman
Ebtehal Alroomi
Salma Alajmi
Tarek Mahmoud
Jude Yagan

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2026.1808461

1,389 views

Editorial

Published on 28 Jul 2025

Editorial: Safety of corticosteroids in respiratory medicine

in Clinical Drug Safety

Semra Bilaçeroğlu

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2025.1656299

4,318 views

Review

Published on 24 Apr 2025

Corticosteroids in lung cancer

in Clinical Drug Safety

Vesna Ćeriman Krstić
Milija Gajić
Leonida Djukanović
Dragana Jovanović

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2025.1528468

12,605 views
4 citations

Original Research

Published on 13 Mar 2025

Developing decision support algorithm for hypertension medications for use in a digital therapeutic system

in Clinical Drug Safety

Jeannie K. Lee
J. Skye Nicholas
Amani Albadawi
Kathleen C. Insel

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2025.1476998

4,890 views

Original Research

Published on 13 May 2024

Progressive multifocal leukoencephalopathy reports in rheumatoid arthritis concerning different treatment patterns-an exploratory assessment using the food and drug administration adverse event reporting system

in Clinical Drug Safety

Takeshi Honma
Kenji Onda
Koichi Masuyama

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2024.1334468

5,060 views
2 citations

Editorial

Published on 05 Feb 2024

Editorial: Treatment of comorbidities of asthma and its safety

in Clinical Drug Safety

Serghei Covantsev
Alexandru Corlateanu

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2024.1366847

2,270 views

Review

Published on 14 Dec 2023

Safety of corticosteroid therapy in sarcoidosis treatment

in Clinical Drug Safety

Alessandro Di Marco Berardino
Federico Mei
Lina Zuccatosta

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2023.1319931

7,025 views
1 citation

Review

Published on 07 Nov 2023

Promising treatment biomarkers in asthma

in Clinical Drug Safety

Barbara Bonnesen
Jens-Ulrik S. Jensen
Alexander G. Mathioudakis
Alexandru Corlateanu
Pradeesh Sivapalan

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2023.1291471

6,236 views
9 citations

Mini Review

Published on 16 Feb 2023

Balancing the evidence: An update on analgesic use in rheumatic and musculoskeletal diseases

in Clinical Drug Safety

Yun-Ting Huang
Craig McCarthy
Meghna Jani

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2023.1117674

6,974 views
8 citations

Original Research

Published on 09 Jan 2023

Adverse events in rheumatoid arthritis patients under antimalarial treatment—Is there cardiovascular compromise?

in Clinical Drug Safety

Pedro Santos-Moreno
Linda Ibatá
Susan Martínez
Gabriel-Santiago Rodríguez-Vargas
Laura Villarreal
Pedro Rodríguez
Wilberto Rivero
Fernando Rodríguez-Florido
Adriana Rojas-Villarraga

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2022.1044696

4,010 views
1 citation

Review

Published on 23 Dec 2022

Deprescribing as a strategy for improving safety of medicines in older people: Clinical and regulatory perspective

in Clinical Drug Safety

Salvatore Crisafulli
Elisabetta Poluzzi
Carlotta Lunghi
Vincenzo Di Francesco
Luca Pellizzari
Luca Pasina
Chiara Elli
Francesco Trotta
Agnese Cangini
Caterina Trevisan

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2022.1011701

12,169 views
26 citations

Original Research

Published on 19 Oct 2022

Putting external validation performance of major bleeding risk models into context

in Clinical Drug Safety

Clair Blacketer
Jenna M. Reps
Lu Wang
Patrick B. Ryan
Zhong Yuan

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2022.1034677

2,313 views

Specialty Grand Challenge

Published on 05 Apr 2022

Current Status and Future Challenges in the Treatment of Rheumatic Diseases

in Clinical Drug Safety

Enrique R. Soriano

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2022.881556

6,332 views
8 citations

Specialty Grand Challenge

Published on 29 Oct 2021

Moving to a Personalized Approach in Respiratory Medicine. From Academic Research to Regulatory Intervention

in Clinical Drug Safety

Mario Cazzola

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2021.752581

3,595 views
6 citations

21 articles

articles

Global patterns and trends in spontaneous reporting systems: VigiBase, FAERS, VAERS, and JADER

Psychotropic dispensing in Greek adolescents and young adults: national trends and regional variation

Deprescribing and Anti-CGRP preventive therapy in medication-overuse headache associated with migraine: pathophysiological rationale and single-center real world evidence

Safety profile of small interfering RNA therapeutics: a systematic review and meta-analysis of randomized controlled trials

The cutaneous mirror: leveraging drug-induced skin phenotypes as early visual risk signals for systemic toxicity, a comprehensive review

Comprehensive pharmacovigilance assessment of pairwise drug–drug interactions and acute pancreatitis in the FDA adverse event reporting system: focus on incretin-based drugs

Modafinil and abnormal bleeding in a young lady with narcolepsy: a case report

Colistin use and outcomes in Kuwait public hospitals

Editorial: Safety of corticosteroids in respiratory medicine

Corticosteroids in lung cancer

Developing decision support algorithm for hypertension medications for use in a digital therapeutic system

Progressive multifocal leukoencephalopathy reports in rheumatoid arthritis concerning different treatment patterns-an exploratory assessment using the food and drug administration adverse event reporting system

Editorial: Treatment of comorbidities of asthma and its safety

Safety of corticosteroid therapy in sarcoidosis treatment

Promising treatment biomarkers in asthma

Balancing the evidence: An update on analgesic use in rheumatic and musculoskeletal diseases

Adverse events in rheumatoid arthritis patients under antimalarial treatment—Is there cardiovascular compromise?

Deprescribing as a strategy for improving safety of medicines in older people: Clinical and regulatory perspective

Putting external validation performance of major bleeding risk models into context

Current Status and Future Challenges in the Treatment of Rheumatic Diseases

Moving to a Personalized Approach in Respiratory Medicine. From Academic Research to Regulatory Intervention