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ORIGINAL RESEARCH article

Front. Endocrinol.

Sec. Clinical Diabetes

Volume 16 - 2025 | doi: 10.3389/fendo.2025.1471608

The Relationship between abdominal fat and sleep quality after Combined Exercise in patients with type 2 diabetes mellitus

Provisionally accepted
Jingxian  FangJingxian FangSui-Jun  WangSui-Jun Wang*Jian  MengJian MengYue-Xia  HanYue-Xia HanYu  HanYu HanFang  HuangFang HuangHui-Ming  ZouHui-Ming ZouQing  GuQing GuXue  HuXue Hu
  • Shanghai Shidong Hospital of Yangpu District, Shanghai, China

The final, formatted version of the article will be published soon.

Background: Exercise holds promise as a non-pharmacological intervention for improving sleep quality. Therefore, this study investigated the potential relationship between abdominal fat and sleep quality after combined exercise in patients with T2DM (Type 2 diabetes mellitus).A total of 100 adults with T2DM (52 women, 48 men), aged 55-75years, were enrolled in the study who were sufficiently active and physically fit were recruited and were randomized equally into four groups: a control group, an AEX group (aerobic exercise), a REX group (resistance exercise) and a COMB group (combination exercise). Patient sleep monitoring reports were collected using a smart bracelet. After 12 weeks of intervention, the Pittsburgh Sleep Quality Index (PSQI) total score, total sleep time, sleep efficiency, time to reawakening, BMI (body mass index), FBG (fasting blood glucose), HOMA-IR (insulin resistance index), HbA1c (glycosylated hemoglobin), VAT (visceral adipose tissue), SAT (subcutaneous adipose tissue), and LBM (lean body mass) were compared among the four groups.All exercise training programs improved the PSQI score in patients with type 2 diabetes. COMB is the only training that improves objective sleep quality and quantity, including total sleep time, sleep efficiency, and wake time after sleep onset. Conclusion: A comprehensive exercise program to reduce abdominal fat can benefit metabolic and sleep health in people with type 2 diabetes. KEYWORDS: Type 2 diabetes mellitus, exercise, VAT (visceral adipose tissue), SAT (subcutaneous adipose tissue), sleep quality

Keywords: type 2 diabetes mellitus, Exercise, VAT (visceral adipose tissue), SAT (subcutaneous adipose tissue), sleep quality

Received: 29 Jul 2024; Accepted: 06 Jun 2025.

Copyright: © 2025 Fang, Wang, Meng, Han, Han, Huang, Zou, Gu and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Sui-Jun Wang, Shanghai Shidong Hospital of Yangpu District, Shanghai, China

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