REVIEW article
Front. Endocrinol.
Sec. Cardiovascular Endocrinology
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1532565
Therapeutic potential of traditional Chinese medicine in diabetic cardiomyopathy: a review
Provisionally accepted
- 1Xiangtan Central Hospital, Xiangtan, China
- 2Changsha Medical University, Changsha, Hunan Province, China
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Diabetic cardiomyopathy (DCM) is a common cardiovascular complication that could lead to changes in cardiac structure and function. It is one of the leading causes of death in diabetic patients. Due to the complex pathogenesis of DCM, there is currently no specific drug or prophylactic agent to treat DCM, so there is an urgent need to identify new therapeutic agents or complementary and alternative therapies for DCM. Although Traditional Chinese medicine (TCM) has some limitations, it has the unique advantages of multi-level, multi-target and few side effects, which could effectively deal with the complex pathological mechanism of DCM.Growing evidence suggests that inflammation, oxidative stress, myocardial fibrosis and autophagy are the main pathological mechanisms of DCM.This study will shed light on the prospects of TCM treatment of DCM from the above perspective in order to provide more ideas and evidence for the 2 clinical use of TCM for the prevention and treatment of DCM.
Keywords: Diabetic cardiomyopathy, Traditional Chinese Medicine, Inflammation, Oxidative Stress, Myocardial fibrosis, Autophagy
Received: 22 Nov 2024; Accepted: 07 Jul 2025.
Copyright: © 2025 Li, Liu, Liu, Xing, Liu, Wu and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Wencan Li, Xiangtan Central Hospital, Xiangtan, China
Jiani Zhang, Xiangtan Central Hospital, Xiangtan, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.