Clinical and radiographical analysis of percutaneous kyphoplasty with multi-point cement anchoring technique for preventing bone cement displacement in Kümmell's disease of stage I and II

Heng Wu¹Xiao Dai¹Hao Liu¹Xiang Yang¹Shenao Liu¹Shuang Xu¹Hao Chi²Yuquan Chen³Song Wang^1*

• ¹Department of Orthopedics, the Affiliated Hospital of Southwest Medical University Luzhou 646000, China, Luzhou, China
• ²Clinical Medical College, Southwest Medical University, Luzhou 646000, China, Luzhou, Sichuan Province, China
• ³School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing & Health Sciences, Monash University, Melbourne, Victoria, Australia

The present study introduced a novel technique called percutaneous kyphoplasty with multi-point cement anchoring technique (A-PKP) to prevent bone cement displacement in patients with stage I and II Kümmell's disease (KD).Methods: A total of 82 patients with stage I and II KD were treated with PKP in our hospital from April 2020 to October 2022. The patients were divided into two groups: A-PKP group (N=39) where the Kirschner needle was used for the multi-point cement anchoring technique, and conventional transverse process-pedicle percutaneous kyphoplasty group (T-PKP group; N=43) where the Kirschner needle was not used. The operation time, volume of cement, VAS score, ODI score, cement distribution pattern and score, bone cement leakage, adjacent vertebra fracture, and bone cement displacement were compared between the two groups. A logistic regression model was used to evaluate the association between outcome variables and vertebral fractures, as well as to identify potential protective and risk factors following kyphoplasty.Results: All patients in both groups were operated successfully, with no serious complications reported. Compared with T-PKP patients, A-PKP patients had longer operation time (39.7±4.86 min vs. 34.5±3.18 min, P < 0.05), greater volume of cement (5.1±0.41 ml vs. 4.3±0.27 ml, P < 0.05), greater improvement in Visual Analog Scale (2.0±0.48, 1.92±0.72 vs. 3.0±0.10, 3.1±0.62, P < 0.05) and Oswestry Disability Index scores (17.9±2.38, 14.8±2.02 vs. 20.2±3.31, 17.2±2.55, P < 0.05) during follow-ups, more spongy cement configuration with higher distribution scores (10.0±1.17 vs. 7.74±1.08, P < 0.05), lower incidence of bone cement leakage (20.5% vs. 27.9%, P > 0.05), and lower rate of adjacent vertebra fractures (5.1% vs. 18.6%, P < 0.05) and bone cement displacement (2.5% vs. 20.9%, P < 0.05). The logistic regression results reveal that bone cement distribution score (OR= 0.355, 95% CI 0.171-0.734, P=0.005) acts as protective factor following kyphoplasty.The A-PKP technique appears to be a safer and more effective alternative for patients with stage I and II KD. It effectively alleviates pain, enhances cement diffusion, and minimizes the risk of bone cement displacement compared with the T-PKP.