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REVIEW article

Front. Endocrinol.

Sec. Translational and Clinical Endocrinology

Volume 16 - 2025 | doi: 10.3389/fendo.2025.1561711

Global Research on Endocrine Disruptors as Emerging Hazards for Human Health and the Environment

Provisionally accepted
Doris  KlingelhöferDoris Klingelhöfer*Markus  BraunMarkus BraunJanis  DrögeJanis DrögeDörthe  BrüggmannDörthe BrüggmannDavid  A. GronebergDavid A. Groneberg
  • Goethe University Frankfurt, Frankfurt, Germany

The final, formatted version of the article will be published soon.

Endocrine disruptors (EDs) contaminate nearly every ecosystem and are significantly associated with different neurological and neurodevelopmental disorders. To date, there is no comprehensive literature on global publication efforts. Since there are many unknown substances, modes of action, and risks of EDs, it is necessary to provide detailed insight into global publication patterns from temporal, regional, and socioeconomic perspectives. Hence, this review article provides background information for all stakeholders, from scientists to clinicians and policymakers. A disproportionate increase in research activity was observed, mainly from the USA and China, with a strong north-south divide. Multi-disciplinarity is characteristic, with a trend toward an ecological focus. Low-and middle-income economies are underrepresented in research on EDs. Therefore, global research needs to be refocused and expanded to more global approaches that take inspiration from the few successful collaborations with their synergistic effects.

Keywords: bisphenol A, Endocrine diseases, Neurological Diseases, pharmaceuticals, estrogen, Thyroid Hormones

Received: 16 Jan 2025; Accepted: 26 May 2025.

Copyright: © 2025 Klingelhöfer, Braun, Dröge, Brüggmann and Groneberg. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Doris Klingelhöfer, Goethe University Frankfurt, Frankfurt, Germany

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