ORIGINAL RESEARCH article
Front. Endocrinol.
Sec. Clinical Diabetes
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1573581
Chinese burdens and trends of diabetic retinopathy 1990-2021 and 15 years forecast: results from the Global Burden of Disease Study 2021.
Provisionally accepted
- 1The Second Affiliated Hospital of Anhui Medical University, Hefei, China
- 2Lu'an Hospital Affiliated to Anhui Medical University, Lu'an, China
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Objectives: To assess the Chinese burden of diabetic retinopathy (DR) between 1990 and 2021, considering variations by year, age, and gender, as well as to forecast the trends over the next 15 years.We evaluated the burden of DR in China based on data from the GBD 2021, examining prevalence, years lived with disability (YLDs), age-standardized YLDs rates (ASYR), and age-standardized prevalence rates (ASPR) over the period 1990 to 2021. Furthermore, we utilized joinpoint analysis and the Bayesian ageperiod-cohort model to explore the epidemiological patterns of the disease and forecast its impact for the years 2022 to 2036.In 2021, the number of YLDs and prevalence attributed to DR were 86,317 (95% UI: 56,595 to 125,565) and 1.37 million (95% UI: 1.04 to 1.78), respectively.Over the period 1990 to 2021, the AAPC of ASYR and ASPR for DR rose by 0.71 (95% CI: 0.28, 1.14) and 0.43 (95% CI: 0.20, 0.66) in China. Older adults and women experienced a greater burden. Aging and demographic changes are key risk factors for DR, and future trends suggest a decrease in ASYR and ASPR.The Chinese burden of DR has increased during the years 1990 to 2021.Despite the anticipated decline in the burden of DR between 2022 and 2036, the importance of bolstering efforts in DR prevention and control should not be underestimated.
Keywords: Age-standardized rates, Blindness, Vision Loss, Diabetic Retinopathy, years
Received: 12 Feb 2025; Accepted: 22 Apr 2025.
Copyright: © 2025 Jiang, He, Zhu and Tao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Chun Jiang, The Second Affiliated Hospital of Anhui Medical University, Hefei, China
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