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ORIGINAL RESEARCH article

Front. Endocrinol.

Sec. Clinical Diabetes

Volume 16 - 2025 | doi: 10.3389/fendo.2025.1601883

Enhanced Diabetes Prediction Using Skip-Gated Recurrent Unit with Gradient Clipping Approach

Provisionally accepted
Suhas  Kamshetty ChinnababuSuhas Kamshetty Chinnababu1Ananda Babu  JayachandraAnanda Babu Jayachandra2Swathi  Holalu YogeshSwathi Holalu Yogesh2Mohamed  AbouhawwashMohamed Abouhawwash3Doaa  Sami KhafagaDoaa Sami Khafaga4Eman  Abdullah AldakheelEman Abdullah Aldakheel4*Vinaykumar  VajjanakurikeVinaykumar Vajjanakurike2
  • 1Channabasaveshwara Institute of Technology, Tumkur, Karnataka, India
  • 2Visvesvaraya Technological University, Belgaum, Karnataka, India
  • 3King Fahd University of Petroleum and Minerals, Dhahran, Ash Sharqiyah, Saudi Arabia
  • 4Department of Computer Sciences, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia

The final, formatted version of the article will be published soon.

Diabetes mellitus is metabolic disorder categorized using hyperglycemia that results from a inadequate of body for secreting and responding to insulin. Disease prediction using various Machine Learning (ML) approaches has gained attention because of its potential for early detection. However, it is a challenging task for ML-based algorithms to capture the long-term dependencies like glucose levels in the diabetes data. Hence, this research developed the Skip-Gated Recurrent Unit (Skip-GRU) with Gradient Clipping (GC) approach which is a Deep Learning (DL) based approach to predict diabetes effectively. The Skip-GRU network effectively captures the long-term dependencies, and it ignores the unnecessary features and provides only the relevant features for diabetes prediction. The GC technique is used during the training process of Skip-GRU network that mitigate the exploding gradients issue and help to predict diabetes effectively. The proposed Skip-GRU with GC approach achieved 98.23% accuracy on a PIMA dataset and 97.65% accuracy on a LMCH dataset. The proposed approach effectively predicts diabetes while comparing with existing conventional ML-based approaches.

Keywords: deep learning, Diabetes Mellitus, gradient clipping, machine learning, Long-term dependencies, skip-gated recurrent unit

Received: 08 Apr 2025; Accepted: 11 Jul 2025.

Copyright: © 2025 Kamshetty Chinnababu, Jayachandra, Yogesh, Abouhawwash, Khafaga, Aldakheel and Vajjanakurike. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Eman Abdullah Aldakheel, Department of Computer Sciences, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia

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