EDITORIAL article
Front. Endocrinol.
Sec. Systems Endocrinology
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1620522
This article is part of the Research TopicGenetics and multi-omics approach in metabolic liver disordersView all 7 articles
Editorial: Genetics and multi-omics approach in metabolic liver disorders
Provisionally accepted
- 1Universidad Autónoma de Baja California, Tijuana, Tijuana, Mexico
- 2Department of Pharmaceutical Sciences, University of New Mexico Health Sciences, Albuquerque, United States
- 3University of North Carolina, Chapel Hill, United States
- 4University of California, Los Angeles, United States
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Genetics and approach in metabolic liver disorders 32 Liver are major causes of morbidity mortality in developing and developed countries, 33 accounting for deaths annually attributable to organic and systemic complications [1]. In 34 addition to viral hepatitis and alcohol abuse, nonalcoholic fatty liver disease (NAFLD) or, more 35 recently renamed as metabolic dysfunction-associated steatotic liver disease (MASLD), is one of the 36 most common causes of chronic liver disease worldwide, which is closely linked to obesity, 37 metabolic syndrome, and type 2 diabetes [2]. Lipid metabolism disorders, insulin resistance and 38 dysregulation of cytokines/adipokines are implicated in the development of NAFLD/MASLD, also 39 contributing to its evolution from steatosis to steatohepatitis, cirrhosis, and even hepatocellular 40 carcinoma [3]. 41The pathogenesis of NAFLD The authors declare that no financial support was granted for the research, authorship, and/or 99 publication of this article. 100
Keywords: Liver disorders, NAFLD/MASLD, Genetics, multi-omics, bioinformatics, precision medicine
Received: 29 Apr 2025; Accepted: 08 May 2025.
Copyright: © 2025 Ramos-Lopez, Paramasivam, Pandey and Chandrakumar. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Omar Ramos-Lopez, Universidad Autónoma de Baja California, Tijuana, Tijuana, Mexico
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